Evidence map›Paper›PMID 38203597›Full record

ArticleInternational journal of molecular sciences2023

CXCL13 in Cerebrospinal Fluid: Clinical Value in a Large Cross-Sectional Study.

Deborah Katharina Erhart, Veronika Klose, Tatjana Schäper, Hayrettin Tumani, Makbule Senel

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
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  6. Article
  7. The utility of CXCL13 and circulating CXCR5Frontiers in immunology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Deborah Katharina ErhartDepartment of Neurology, University Hospital of Ulm, Oberer Eselsberg 45, 89081 Ulm, Germany.ORCID 0000-0002-3003-4119
Veronika KloseGerman Center for Neurodegenerative Diseases (DZNE)-Ulm, Oberer Eselsberg 45, 89081 Ulm, Germany.ORCID 0009-0004-1597-2571
Tatjana SchäperDepartment of Neurology, University Hospital of Ulm, Oberer Eselsberg 45, 89081 Ulm, Germany.
Hayrettin TumaniDepartment of Neurology, University Hospital of Ulm, Oberer Eselsberg 45, 89081 Ulm, Germany.ORCID 0000-0002-1647-6201
Makbule SenelDepartment of Neurology, University Hospital of Ulm, Oberer Eselsberg 45, 89081 Ulm, Germany.ORCID 0000-0002-2737-7495
University Hospital Ulm · DEGerman Center for Neurodegenerative Diseases · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

C-X-C-motif chemokine ligand 13 (CXCL13) in cerebrospinal fluid (CSF) is increasingly used in clinical routines, although its diagnostic specificity and divergent cut-off values have been defined so far mainly for neuroborreliosis. Our aim was to evaluate the value of CSF-CXCL13 as a diagnostic and treatment response marker and its role as an activity marker in a larger disease spectrum, including neuroborreliosis and other neuroinflammatory and malignant CNS-disorders. Patients who received a diagnostic lumbar puncture (LP) (

Indexed as

Multiple SclerosisNeurosyphilisChemokine CXCL13Cross-Sectional StudiesHumansRetrospective StudiesSpinal PunctureSyndromeChemokine CXCL13CXCL13 protein, humancerebrospinal fluidCNS-inflammatory diseasesCXCL13neuroborreliosis

Identifiers

PMID38203597
PMCPMC10779058
OpenAlexW4390347526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.