Evidence map›Paper›PMID 38203575›Full record

ArticleInternational journal of molecular sciences2023

Altered Gene Expression of IL-35 and IL-36α in the Skin of Patients with Atopic Dermatitis.

Weronika Zysk, Krzysztof Sitko, Stefan Tukaj, Anna Zaryczańska, Magdalena Trzeciak

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
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  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Weronika ZyskDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, 80-214 Gdansk, Poland.ORCID 0000-0001-7439-8881
Krzysztof SitkoDepartment of Molecular Biology, Faculty of Biology, University of Gdansk, 80-308 Gdansk, Poland.ORCID 0000-0001-7842-7555
Stefan TukajDepartment of Molecular Biology, Faculty of Biology, University of Gdansk, 80-308 Gdansk, Poland.ORCID 0000-0003-1288-0511
Anna ZaryczańskaDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, 80-214 Gdansk, Poland.ORCID 0000-0003-0988-6824
Magdalena TrzeciakDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, 80-214 Gdansk, Poland.ORCID 0000-0002-8206-8441
Gdańsk Medical University · PLUniversity of Gdańsk · PL

Funding

National Science Center 2020/37/N/NZ5/04208National Science Center 2020/39/B/NZ6/00357
6 · The paper itself

Abstract

A comprehensive understanding of atopic dermatitis (AD) pathogenesis is desired, especially in the current era of novel biologics and small molecule drugs. In recent years, new cytokines have emerged that may play a significant role in the pathogenesis of AD. Using the tape stripping (TS) method, this study analyzed the gene expression of IL-35 and IL-36α in lesional and nonlesional AD skin compared with healthy skin and their association with the clinical features of AD among the Polish population. Ten AD patients and seven healthy individuals were enrolled. The lesional skin of the AD patients showed significantly higher expression levels of IL-35 compared to healthy skin (

Indexed as

Biological ProductsDermatitis, AtopicGene ExpressionHumansInterleukin-1Interleukin-12 Subunit p35InterleukinsSkinBiological ProductsIL12A protein, humanIL36A protein, humanInterleukin-1Interleukin-12 Subunit p35Interleukinsatopic dermatitisbiomarkerskin immunologytape stripping

Identifiers

PMID38203575
PMCPMC10779293
OpenAlexW4390341287

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.