Evidence map›Paper›PMID 38203281›Full record

ReviewInternational journal of molecular sciences2023

Current Review of the Function and Regulation of Tuberoinfundibular Dopamine Neurons.

Xiaojun Qi-Lytle, Sarah Sayers, Edward J Wagner

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Xiaojun Qi-LytleDepartment of Medical Education, Geisinger Commonwealth School of Medicine, 525 Pine St., Scranton, PA 18509, USA.
Sarah SayersDepartment of Basic Medical Science, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, 309 E. Second St., Pomona, CA 91766, USA.ORCID 0000-0002-6189-3303
Edward J WagnerDepartment of Basic Medical Science, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, 309 E. Second St., Pomona, CA 91766, USA.
Western University of Health Sciences · USGeisinger Commonwealth School of Medicine · US

Funding

Sex Differences in the Cannabioid Regulation of Energy HomeostasisR15DA024314 · NIDA · WESTERN UNIVERSITY OF HEALTH SCIENCES · PI WAGNER, EDWARD J · 2008 to 2020
$1.5M
NIDA NIH HHS R15 DA024314NIH HHS DA024314
6 · The paper itself

Abstract

Tuberoinfundibular dopamine (TIDA) neurons have cell bodies located in the arcuate nucleus of the mediobasal hypothalamus. They project to the external zone of the median eminence, and the dopamine (DA) released there is carried by the hypophysial portal vasculature to the anterior pituitary. The DA then activates D2 receptors to inhibit prolactin (PRL) secretion from lactotrophs. The TIDA neuronal population is the principal regulatory factor controlling PRL secretion. The neuroendocrine role subserved by TIDA neurons sets them apart from other dopaminergic populations like the nigrostriatal and mesolimbic DA neurons. TIDA neurons exhibit intrinsic oscillatory fluctuations in their membrane potential that give rise to phasic firing and bursting activity. TIDA neuronal activity is sexually differentiated and modulated by gonadal hormones and PRL, as well as an array of small molecule and peptide neurotransmitters. This review covers these characteristics.

Indexed as

DopamineDopaminergic NeuronsArcuate Nucleus of HypothalamusCell CommunicationCell DifferentiationDopaminedopamineestradiolGABAglutamatelactationopioidsprolactinthyrotropin releasing hormoneTIDA neurons

Identifiers

PMID38203281
PMCPMC10778701
OpenAlexW4390057516

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.