Evidence map›Paper›PMID 38203247›Full record

ArticleInternational journal of molecular sciences2023

Development of a Predictive Model for Optimization of Embryo Transfer Timing Using Blood-Based microRNA Expression Profile.

Ming-Jer Chen, An Hsu, Pei-Yi Lin, Yu-Ling Chen, Ko-Wen Wu, Kuan-Chun Chen, Tiffany Wang, Yu-Chiao Yi, Hsiao-Fan Kung, Jui-Chun Chang and 9 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. MicroRNAs as Biomarkers and Therapeutic Targets in Female Infertility.International journal of molecular sciences · 2024
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Ming-Jer ChenDivision of Reproductive Endocrinology and Infertility, Department of Obstetrics Gynecology & Women's Health, Taichung Veterans General Hospital, Taichung 40764, Taiwan.ORCID 0000-0002-5618-1969
An HsuInti Labs, Hsinchu 30261, Taiwan.ORCID 0000-0002-3146-7282
Pei-Yi LinInti Labs, Hsinchu 30261, Taiwan.
Yu-Ling ChenInti Labs, Hsinchu 30261, Taiwan.
Ko-Wen WuInti Labs, Hsinchu 30261, Taiwan.ORCID 0009-0007-1718-0377
Kuan-Chun ChenInti Labs, Hsinchu 30261, Taiwan.
Tiffany WangInti Labs, Hsinchu 30261, Taiwan.
Yu-Chiao YiDivision of Reproductive Endocrinology and Infertility, Department of Obstetrics Gynecology & Women's Health, Taichung Veterans General Hospital, Taichung 40764, Taiwan.
Hsiao-Fan KungDivision of Reproductive Endocrinology and Infertility, Department of Obstetrics Gynecology & Women's Health, Taichung Veterans General Hospital, Taichung 40764, Taiwan.
Jui-Chun ChangDivision of Reproductive Endocrinology and Infertility, Department of Obstetrics Gynecology & Women's Health, Taichung Veterans General Hospital, Taichung 40764, Taiwan.
Wen-Jui YangTaiwan IVF Group Center for Reproductive Medicine and Infertility, Hsinchu 30274, Taiwan.
Farn LuTaiwan IVF Group Center for Reproductive Medicine and Infertility, Hsinchu 30274, Taiwan.
Hwa-Fen GuuDivision of Reproductive Endocrinology and Infertility, Department of Obstetrics Gynecology & Women's Health, Taichung Veterans General Hospital, Taichung 40764, Taiwan.
Ya-Fang ChenDivision of Reproductive Endocrinology and Infertility, Department of Obstetrics Gynecology & Women's Health, Taichung Veterans General Hospital, Taichung 40764, Taiwan.
Shih-Ting ChuanDivision of Reproductive Endocrinology and Infertility, Department of Obstetrics Gynecology & Women's Health, Taichung Veterans General Hospital, Taichung 40764, Taiwan.
Li-Yu ChenDivision of Reproductive Endocrinology and Infertility, Department of Obstetrics Gynecology & Women's Health, Taichung Veterans General Hospital, Taichung 40764, Taiwan.
Ching-Hung ChenTaiwan IVF Group Center for Reproductive Medicine and Infertility, Hsinchu 30274, Taiwan.ORCID 0000-0003-1397-8334
Pok Eric YangInti Labs, Hsinchu 30261, Taiwan.
Jack Yu-Jen HuangTaiwan IVF Group Center for Reproductive Medicine and Infertility, Hsinchu 30274, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) can regulate the expression of genes involved in the establishment of the window of implantation (WOI) in the endometrium. Recent studies indicated that cell-free miRNAs in uterine fluid and blood samples could act as alternative and non-invasive sample types for endometrial receptivity analysis. In this study, we attempt to systematically evaluate whether the expression levels of cell-free microRNAs in blood samples could be used as non-invasive biomarkers for assessing endometrial receptivity status. We profiled the miRNA expression levels of 111 blood samples using next-generation sequencing to establish a predictive model for the assessment of endometrial receptivity status. This model was validated with an independent dataset (

Indexed as

Circulating MicroRNAMicroRNAsEmbryo ImplantationEmbryo TransferEndometriumFemaleHumansCirculating MicroRNAMicroRNAsbloodcell-free microRNAendometrial receptivitynext-generation sequencingnon-invasive biomarkers

Identifiers

PMID38203247
PMCPMC10779357

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.