Evidence map›Paper›PMID 38203225›Full record

ArticleInternational journal of molecular sciences2023

3'dNTP Binding Is Modulated during Primer Synthesis and Translesion by Human PrimPol.

Cristina Velázquez-Ruiz, Luis Blanco, María Isabel Martínez-Jiménez

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Mouse PrimPol Outperforms Its Human Counterpart as a Robust DNA Primase.International journal of molecular sciences · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Cristina Velázquez-RuizCentro de Biología Molecular Severo Ochoa, (CSIC-UAM), c/Nicolás Cabrera 1, Cantoblanco, 28049 Madrid, Spain.ORCID 0000-0003-1117-6944
Luis BlancoCentro de Biología Molecular Severo Ochoa, (CSIC-UAM), c/Nicolás Cabrera 1, Cantoblanco, 28049 Madrid, Spain.ORCID 0000-0001-5558-4435
María Isabel Martínez-JiménezCentro de Biología Molecular Severo Ochoa, (CSIC-UAM), c/Nicolás Cabrera 1, Cantoblanco, 28049 Madrid, Spain.ORCID 0000-0002-7653-2877
Centro de Biología Molecular Severo Ochoa · ES

Funding

Agencia Estatal de Investigación PID2021-125966OB-I00
6 · The paper itself

Abstract

PrimPol is a DNA primase/polymerase from the Archaeo-Eukaryotic Primase (AEP) superfamily that enables the progression of stalled replication forks by synthesizing DNA primers ahead of blocking lesions or abnormal structures in the ssDNA template. PrimPol's active site is formed by three AEP-conserved motifs: A, B and C. Motifs A and C of human PrimPol (

Indexed as

DNA PrimaseNucleotidyltransferasesCatalysisCognitionDNA-Directed DNA PolymeraseDNA PrimersHumansMultifunctional EnzymesNucleotidesDNA-Directed DNA PolymeraseDNA PrimaseDNA PrimersMultifunctional EnzymesNucleotidesNucleotidyltransferasesPrimPol protein, human3′site dNTP ligandsAEPAEP motif Bhuman PrimPolTLS

Identifiers

PMID38203225
PMCPMC10778844
OpenAlexW4389977420

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.