Evidence map›Paper›PMID 38202861›Full record

ReviewMolecules (Basel, Switzerland)2024

Recent Advances in Chemistry and Antioxidant/Anticancer Biology of Monoterpene and Meroterpenoid Natural Product.

Benedict J Barras, Taotao Ling, Fatima Rivas

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Terpenoids as modulators of autophagy-senescence crosstalk in lung cancer.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2026
    Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Monoterpene Hydroxy Lactones Isolated fromMolecules (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Benedict J BarrasDepartment of Chemistry, Louisiana State University, 133 Choppin Hall, Baton Rouge, LA 70803, USA.ORCID 0009-0005-9175-0038
Taotao LingDepartment of Chemistry, Louisiana State University, 133 Choppin Hall, Baton Rouge, LA 70803, USA.
Fatima RivasDepartment of Chemistry, Louisiana State University, 133 Choppin Hall, Baton Rouge, LA 70803, USA.ORCID 0000-0003-3643-2035

Funding

Elucidating the mode of action of the abietanes to develop potential therapeutic agents_supplementR15GM148983 · NIGMS · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI RIVAS, FATIMA R · 2022 to 2023
$467k
NIGMS NIH HHS R15 GM148983
6 · The paper itself

Abstract

Monoterpenes and meroterpenes are two large classes of isoprene-based molecules produced by terrestrial plants and unicellular organisms as diverse secondary metabolites. The global rising incidence of cancer has led to a renewed interest in natural products. These monoterpenes and meroterpenes represent a novel source of molecular scaffolds that can serve as medicinal chemistry platforms for the development of potential preclinical leads. Furthermore, some of these natural products are either abundant, or their synthetic strategies are scalable as it will be indicated here, facilitating their derivatization to expand their scope in drug discovery. This review is a collection of representative updates (from 2016-2023) in biologically active monoterpene and meroterpenoid natural products and focuses on the recent findings of the pharmacological potential of these bioactive compounds as well as the newly developed synthetic strategies employed to access them. Particular emphasis will be placed on the anticancer and antioxidant potential of these compounds in order to raise knowledge for further investigations into the development of potential anti-cancer therapeutics. The mounting experimental evidence from various research groups across the globe regarding the use of these natural products at pre-clinical levels, renders them a fast-track research area worth of attention.

Indexed as

Antineoplastic AgentsBiological ProductsAntioxidantsBiologyMonoterpenesAntineoplastic AgentsAntioxidantsBiological ProductsMonoterpenesanticancer activitymeroterpene natural productsmonoterpenetotal synthesis

Identifiers

PMID38202861
PMCPMC10780832

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.