Evidence map›Paper›PMID 38202779›Full record

ArticleMolecules (Basel, Switzerland)2023

Anti-Trypanosomal Bufadienolides from the Oocytes of the Toad

Candelario Rodriguez, Roberto Ibáñez, Dionisio A Olmedo, Michelle Ng, Carmenza Spadafora, Armando A Durant-Archibold, Marcelino Gutiérrez

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 66% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Candelario RodriguezCentro de Biodiversidad y Descubrimiento de Drogas, Instituto de Investigaciones Científicas y Servicios de Alta Tecnología (INDICASAT-AIP), Panamá 0843-01103, Panama.
Roberto IbáñezSmithsonian Tropical Research Institute, Balboa, Ancon 0843-03092, Panama.ORCID 0000-0001-6118-5780
Dionisio A OlmedoCentro de Investigaciones Farmacognósticas de la Flora Panameña (CIFLORPAN), Facultad de Farmacia, Universidad de Panamá, Panamá 0824-03366, Panama.ORCID 0000-0002-4681-1365
Michelle NgCentro de Biología Celular y Molecular de Enfermedades, INDICASAT AIP, Panamá 0843-01103, Panama.
Carmenza SpadaforaCentro de Biología Celular y Molecular de Enfermedades, INDICASAT AIP, Panamá 0843-01103, Panama.ORCID 0000-0002-3002-9467
Armando A Durant-ArchiboldCentro de Biodiversidad y Descubrimiento de Drogas, Instituto de Investigaciones Científicas y Servicios de Alta Tecnología (INDICASAT-AIP), Panamá 0843-01103, Panama.
Marcelino GutiérrezCentro de Biodiversidad y Descubrimiento de Drogas, Instituto de Investigaciones Científicas y Servicios de Alta Tecnología (INDICASAT-AIP), Panamá 0843-01103, Panama.ORCID 0000-0003-1423-3772
Instituto de Investigaciones Científicas y Servicios de Alta Tecnología · PAUniversidad de Panamá · PAAcharya Nagarjuna University · IN

Funding

Secretaría Nacional de Ciencia, Tecnología e Innovación INDICASAT-BID Program IND-JAL-05
6 · The paper itself

Abstract

Amphibians are widely known as a prolific source of bioactive metabolites. In this work, we isolated and characterized compounds with antiparasitic activity from the oocytes of the toad

Indexed as

BufanolidesChagas DiseaseTrypanosoma cruziAnimalsBufonidaeMolecular Docking SimulationOocytesBufanolidesanti-trypanosomal activitybufadienolidesBufonidaeoocytesRhinella alatatoadsTrypanosoma cruzi

Identifiers

PMID38202779
PMCPMC10779871
OpenAlexW4390395888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.