Evidence map›Paper›PMID 38202694›Full record

ArticleMolecules (Basel, Switzerland)2023

A Qualitative Analysis of Cultured Adventitious Ginseng Root's Chemical Composition and Immunomodulatory Effects.

Hong Chen, Xiangzhu Li, Hang Chi, Zhuo Li, Cuizhu Wang, Qianyun Wang, Hao Feng, Pingya Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Evaluating the Root Extract ofMolecules (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hong ChenSchool of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.
Xiangzhu LiTonghua Herbal Biotechnology, Co., Ltd., Tonghua 134123, China.
Hang ChiTonghua Herbal Biotechnology, Co., Ltd., Tonghua 134123, China.
Zhuo LiSchool of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.
Cuizhu WangSchool of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.ORCID 0000-0002-0694-4059
Qianyun WangSchool of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.
Hao FengCollege of Basic Medicine Sciences, Jilin University, Changchun 130021, China.
Pingya LiSchool of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.
Jilin University · CNShanghai Jiao Tong University · CN

Funding

Jilin Provincial Department of Science and Technology grant No. 20220204025YY
6 · The paper itself

Abstract

The cultivation of ginseng in fields is time-consuming and labor-intensive. Thus, culturing adventitious ginseng root in vitro constitutes an effective approach to accumulating ginsenosides. In this study, we employed UPLC-QTOF-MS to analyze the composition of the cultured adventitious root (cAR) of ginseng, identifying 60 chemical ingredients. We also investigated the immunomodulatory effect of cAR extract using various mouse models. The results demonstrated that the cAR extract showed significant activity in enhancing the immune response in mice. The mechanism underlying the immunomodulatory effect of cAR was analyzed through network pharmacology analysis, revealing potential 'key protein targets', namely TNF, AKT1, IL-6, VEGFA, and IL-1β, affected by potential 'key components', namely the ginsenosides PPT, F1, Rh2, CK, and 20(

Indexed as

GinsenosidesPanaxAnimalsDisease Models, AnimalMicePhosphatidylinositol 3-KinasesPlant ExtractsGinsenosidesPhosphatidylinositol 3-KinasesPlant Extractscultured adventitious root of ginsengginsenosidesimmunomodulatorynetwork pharmacology analysisUPLC-QTOF-MS

Identifiers

PMID38202694
PMCPMC10780104
OpenAlexW4390175398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.