Complex-Forming Properties of the Anti-Inflammatory Sialorphin Derivative Palmitic Acid-Lysine-Lysine-Glutamine-Histidine-Asparagine-Proline-Arginine with Cu(II) Ions in an Aqueous Solution.

Marek Pająk, Elżbieta Kamysz, Karol Sikora, Jakub Fichna, Magdalena Woźniczka

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Protolytic properties and biological activity of spinorphin and its butyric acid derivatives in aqueous solution.Amino acids · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marek PająkDepartment of Physical and Biocoordination Chemistry, Medical University of Lodz, Muszyńskiego 1, 90-151 Lodz, Poland.ORCID 0000-0003-3194-834X

Elżbieta KamyszLaboratory of Chemistry of Biological Macromolecules, Department of Molecular Biotechnology, Faculty of Chemistry, University of Gdańsk, 80-308 Gdańsk, Poland.ORCID 0000-0002-9741-4562

Karol SikoraDepartment of Inorganic Chemistry, Faculty of Pharmacy, Medical University of Gdańsk, Al. Gen. J. Hallera 107, 80-416 Gdańsk, Poland.ORCID 0000-0003-0275-3017

Jakub FichnaDepartment of Biochemistry, Medical University of Lodz, Mazowiecka 5, 92-215 Lodz, Poland.ORCID 0000-0002-8443-4417

Magdalena WoźniczkaDepartment of Physical and Biocoordination Chemistry, Medical University of Lodz, Muszyńskiego 1, 90-151 Lodz, Poland.ORCID 0000-0001-7706-1993

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present work describes the complexation of the anti-inflammatory sialorphin derivative Pal-Lys-Lys-Gln-His-Asn-Pro-Arg (palmitic acid-lysine-lysine-glutamine-histidine-asparagine-proline-arginine) with Cu(II) ions in an aqueous solution, at a temperature of 25.0 ± 0.1 °C, over the whole pH range. The complexing properties were characterized by potentiometric and UV-Vis spectrophotometric methods. The potentiometric method was used to calculate the logarithms of the overall stability constants (log

Indexed as

AsparaginePeptidesProlineAmino AcidsAnti-Inflammatory AgentsArginineGlutamineHistidineIonsLysinePalmitic AcidAmino AcidsAnti-Inflammatory AgentsArginineAsparagineGlutamineHistidineIonsLysinePalmitic AcidPeptidesProlinesialorphinCu(II) complexespalmitic acidpotentiometryprotonation constantsialorphinstability constantUV-Vis spectroscopy

Identifiers

PMID38202673

DOI10.3390/molecules29010090

PMCPMC10779640

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.