ReviewJournal of clinical medicine2024
From Clinical Suspicion to Diagnosis: A Review of Diagnostic Approaches and Challenges in Fungal Keratitis.
Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 24 citations in OpenAlex.
- Fungal keratitis in Germany : Diagnostics, conservative and microsurgical treatment.Die Ophthalmologie · 2026Review
- Clinical profile of microsporidial keratoconjunctivitis in healthy individuals of China -new species and neglected risk factors.Journal of ophthalmic inflammation and infection · 2026Article
- Beauveria bassiana: an emerging pathogen of fungal keratitis.BMC infectious diseases · 2026Article
- Immunotherapy in Ocular Fungal Infections: Advances and Emerging Strategies.Current microbiology · 2026Review
- Colletotrichum fructicola-induced fungal keratitis: a case report and literature review.Journal of ophthalmic inflammation and infection · 2026Article
- Bridging Gaps in Fungal Keratitis Management: Novel Diagnostics, Drug Delivery Systems, and Gene Therapies.AAPS PharmSciTech · 2026Review
- Emerging zoonotic ocular sporotrichosis in southeast Asia: a case series from Thailand and systematic review of regional reports.Journal of ophthalmic inflammation and infection · 2026Article
- A case report of ocular infection caused byAME case reports · 2026Article
- Article
- Unveiling rare fungal pathogens: clinical insights and molecular identification in fungal keratitis cases.International ophthalmology · 2025Article
- Clinical Manifestations, Antifungal Susceptibilities, and Outcome of Ocular Infections Caused byMicroorganisms · 2025Article
- Beauveria bassiana keratitis - the first Hungarian case report.BMC ophthalmology · 2025Article
- Clinical features, microbiological characteristics, and treatment outcomes of fungal keratitis in a tertiary referral hospital in Eastern China.BMC infectious diseases · 2025Article
- Article
- [Fungal keratitis in Germany : Diagnostics, conservative and microsurgical treatment].Die Ophthalmologie · 2025Review
- Review
- New Biomarkers for Patients With Fungal Keratitis From Blood Routine Examination: Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio.Journal of ophthalmology · 2025Article
- Emerging diagnostic modalities in microbial keratitis: Beyond culture and smear.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological SocietyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fungal keratitis is a relatively rare yet severe ocular infection that can lead to profound vision impairment and even permanent vision loss. Rapid and accurate diagnosis plays a crucial role in the effective management of the disease. A patient's history establishes the initial clinical suspicion since it can provide valuable clues to potential predisposing factors and sources of fungal exposure. Regarding the evaluation of the observed symptoms, they are not exclusive to fungal keratitis, but their timeline can aid in distinguishing fungal keratitis from other conditions. Thorough clinical examination of the affected eye with a slit-lamp microscope guides diagnosis because some clinical features are valuable predictors of fungal keratitis. Definitive diagnosis is established through appropriate microbiological investigations. Direct microscopic examination of corneal scrapings or biopsy specimens can assist in the presumptive diagnosis of fungal keratitis, but culture remains the gold standard for diagnosing fungal keratitis. Advanced molecular techniques such as PCR and MALDI-ToF MS are explored for their rapid and sensitive diagnostic capabilities. Non-invasive techniques like in vivo confocal microscopy (IVCM) and optical coherence tomography (OCT) are useful for real-time imaging. Every diagnostic technique has both advantages and drawbacks. Also, the selection of a diagnostic approach can depend on various factors, including the specific clinical context, the availability of resources, and the proficiency of healthcare personnel.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.