Evidence map›Paper›PMID 38202279›Full record

ArticleJournal of clinical medicine2024

Clinical Course and Management of Patients with Emergency Surgery Treated with Direct Oral Anticoagulants or Vitamin K Antagonists-Results of the German Prospective RADOA-Registry.

Jana Last, Eva Herrmann, Ingvild Birschmann, Simone Lindau, Stavros Konstantinides, Oliver Grottke, Ulrike Nowak-Göttl, Barbara Zydek, Christian von Heymann, Ariane Sümnig and 6 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Jana LastCoagulation Research Centre Bethanien Hospital, 63089 Frankfurt, Germany.
Eva HerrmannInstitute of Biostatistics and Mathematical Modelling, Goethe University Frankfurt, 60596 Frankfurt, Germany.ORCID 0000-0002-0662-6675
Ingvild BirschmannInstitute for Laboratory and Transfusion Medicine, Heart and Diabetes Centre, Ruhr University, 44801 Bochum, Germany.
Simone LindauDepartment of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, 60596 Frankfurt, Germany.
Stavros KonstantinidesCenter for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg University Mainz, 55122 Mainz, Germany.
Oliver GrottkeDepartment of Anaesthesiology, RWTH Aachen University Hospital, 52062 Aachen, Germany.
Ulrike Nowak-GöttlInstitute of Clinical Chemistry, Thrombosis & Hemostasis Treatment Centre, University Hospital, Kiel-Lübeck, 24105 Kiel, Germany.
Barbara ZydekCoagulation Research Centre Bethanien Hospital, 63089 Frankfurt, Germany.
Christian von HeymannDepartment of Anaesthesia, Intensive Care Medicine, Emergency Medicine and Pain Therapy, Vivantes Klinikum im Friedrichshain, 10249 Berlin, Germany.
Ariane SümnigInstitute for Transfusions Medicine, Universitätsmedizin Greifswald, 17489 Greifswald, Germany.
Jan Beyer-WestendorfDepartment of Medicine 1, Division of Thrombosis & Hemostasis, Dresden University Clinic, 01307 Dresden, Germany.
Sebastian SchellongMedical Department 2, Municipal Hospital, 01129 Dresden, Germany.
Patrick MeybohmDepartment of Anaesthesiology, Intensive Care, Emergency and Pain Medicine, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.ORCID 0000-0002-2666-8696
Andreas GreinacherInstitute for Transfusions Medicine, Universitätsmedizin Greifswald, 17489 Greifswald, Germany.ORCID 0000-0001-8343-7336
Edelgard Lindhoff-LastCoagulation Research Centre Bethanien Hospital, 63089 Frankfurt, Germany.ORCID 0000-0002-7019-7887
RADOA-Registry Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: The clinical management of anticoagulated patients treated with direct oral anticoagulants (DOAC) or Vitamin K antagonists (VKA) needing emergency surgery is challenging. (2) Methods: The prospective German RADOA registry investigated treatment strategies in DOAC- or VKA-treated patients needing emergency surgery within 24 h after admission. Effectiveness was analysed by clinical endpoints including major bleeding. Primary observation endpoint was in hospital mortality until 30 days after admission. (3) Results: A total of 78 patients were included (DOAC: 44; VKA: 34). Median age was 76 years. Overall, 43% of the DOAC patients and 79% of the VKA patients were treated with prothrombin complex concentrates (PCC) (

Indexed as

direct oral anticoagulantsemergency surgerymajor bleedingprothrombin complex concentratevitamin K antagonists

Identifiers

PMID38202279
PMCPMC10780086

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.