Evidence map›Paper›PMID 38202105›Full record

ReviewJournal of clinical medicine2023

Antithrombotic Therapy Optimization in Patients with Atrial Fibrillation Undergoing Percutaneous Coronary Intervention.

Felice Gragnano, Antonio Capolongo, Antonio Micari, Francesco Costa, Victoria Garcia-Ruiz, Vincenzo De Sio, Fabrizia Terracciano, Arturo Cesaro, Elisabetta Moscarella, Silvio Coletta and 6 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Cost-Effectiveness and Budget Impact Analysis of Radiofrequency Renal Denervation for Uncontrolled and Resistant Hypertension in Italy.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026
    Article
  3. Add-on antiplatelet therapy in anticoagulated patients with atrial fibrillation.International journal of cardiology. Heart & vasculature · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Observational
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 1 country.

Felice GragnanoDepartment of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", 81100 Caserta, Italy.ORCID 0000-0002-6943-278X
Antonio CapolongoDepartment of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", 81100 Caserta, Italy.
Antonio MicariDepartment of Biomedical and Dental Sciences and Morphological and Functional Imaging, University of Messina, 98122 Messina, Italy.
Francesco CostaDepartment of Biomedical and Dental Sciences and Morphological and Functional Imaging, University of Messina, 98122 Messina, Italy.ORCID 0000-0002-3097-2834
Victoria Garcia-RuizDepartment of Cardiology, GIOMI Hospital, 98122 Messina, Italy.
Vincenzo De SioDepartment of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", 81100 Caserta, Italy.
Fabrizia TerraccianoDepartment of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", 81100 Caserta, Italy.
Arturo CesaroDepartment of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", 81100 Caserta, Italy.ORCID 0000-0003-4435-1235
Elisabetta MoscarellaDepartment of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", 81100 Caserta, Italy.
Silvio ColettaDivision of Clinical Cardiology, Azienda Ospedaliera di Rilievo Nazionale "Sant'Anna e San Sebastiano", 81100 Caserta, Italy.ORCID 0000-0002-9282-1003
Pasquale RaucciDivision of Health Technology Assessment, Azienda Ospedaliera di Rilievo Nazionale "Sant'Anna e San Sebastiano", 81100 Caserta, Italy.
Fabio FimianiUnit of Inherited and Rare Cardiovascular Diseases, Azienda Ospedaliera di Rilievo Nazionale Dei Colli, "Vincenzo Monaldi", CCMR Regione Campania, 80138 Naples, Italy.ORCID 0000-0001-9797-8360
Leonardo De LucaDivision of Cardiology, Department of Cardiosciences, Azienda Ospedaliera San Camillo-Forlanini, 00152 Roma, Italy.ORCID 0000-0002-8552-1272
Giuseppe GargiuloDepartment of Advanced Biomedical Sciences, University of Naples Federico II, 80138 Naples, Italy.ORCID 0000-0003-4395-6742
Giuseppe AndòDepartment of Clinical and Experimental Medicine, University of Messina, 98122 Messina, Italy.ORCID 0000-0001-5552-6382
Paolo CalabròDepartment of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", 81100 Caserta, Italy.ORCID 0000-0002-5018-830X
University of Campania "Luigi Vanvitelli" · ITUniversity of Messina · ITOspedale Sant'Anna · ITAzienda Ospedaliera San Camillo-Forlanini · ITRegione Campania · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The antithrombotic management of patients with atrial fibrillation (AF) undergoing percutaneous coronary intervention (PCI) poses numerous challenges. Triple antithrombotic therapy (TAT), which combines dual antiplatelet therapy (DAPT) with oral anticoagulation (OAC), provides anti-ischemic protection but increases the risk of bleeding. Therefore, TAT is generally limited to a short phase (1 week) after PCI, followed by aspirin withdrawal and continuation of 6-12 months of dual antithrombotic therapy (DAT), comprising OAC plus clopidogrel, followed by OAC alone. This pharmacological approach has been shown to mitigate bleeding risk while preserving adequate anti-ischemic efficacy. However, the decision-making process remains complex in elderly patients and those with co-morbidities, significantly influencing ischemic and bleeding risk. In this review, we discuss the available evidence in this area from randomized clinical trials and meta-analyses for post-procedural antithrombotic therapies in patients with non-valvular AF undergoing PCI.

Indexed as

atrial fibrillationbleedingDAPTP2Y12 inhibitorsPCItriple antithrombotic therapy

Identifiers

PMID38202105
PMCPMC10780105
OpenAlexW4390174826

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.