Evidence map›Paper›PMID 38201970›Full record

Trial reportNutrients2023

Effects of Prebiotic Yeast Mannan on Gut Health and Sleep Quality in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Study.

Reiko Tanihiro, Masahiro Yuki, Masaki Sasai, Akane Haseda, Hiroyo Kagami-Katsuyama, Tatsuhiko Hirota, Naoyuki Honma, Jun Nishihira

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Heat-TreatedNutrients · 2025
    Trial
  4. Trial
  5. Review
  6. Review
  7. Article
  8. Microbiome-Based Therapeutics for Insomnia.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Reiko TanihiroCore Technology Laboratories, Asahi Quality and Innovations, Ltd., Moriya 302-0106, Japan.
Masahiro YukiCore Technology Laboratories, Asahi Quality and Innovations, Ltd., Moriya 302-0106, Japan.
Masaki SasaiCore Technology Laboratories, Asahi Quality and Innovations, Ltd., Moriya 302-0106, Japan.
Akane HasedaDepartment of Medical Management and Informatics, Hokkaido Information University, Ebetsu 069-8585, Japan.
Hiroyo Kagami-KatsuyamaDepartment of Medical Management and Informatics, Hokkaido Information University, Ebetsu 069-8585, Japan.
Tatsuhiko HirotaCore Technology Laboratories, Asahi Quality and Innovations, Ltd., Moriya 302-0106, Japan.ORCID 0000-0002-7232-9652
Naoyuki HonmaDepartment of Medical Management and Informatics, Hokkaido Information University, Ebetsu 069-8585, Japan.
Jun NishihiraDepartment of Medical Management and Informatics, Hokkaido Information University, Ebetsu 069-8585, Japan.ORCID 0000-0002-2792-7530
Asahi Breweries (Japan) · JPHokkaido Information University · JP

Funding

Asahi Group Holdings, Ltd. Asahi Quality and Innovationsthe cross-ministerial Strategic Innovation Promotion Program (SIP), "Technologies for Smart Bio-industry and Agriculture" (funding agency: Bio-oriented Technology Research Advanced In-stitution, NARO, Japan) SIP2B
6 · The paper itself

Abstract

Human gut health is closely related to sleep. We aimed to evaluate the efficacy of yeast mannan (YM) in improving bowel habits and sleep quality, along with metabolomics in fecal samples. A total of 40 healthy adults (age range, 22-64 years) with discomfort in defecation were enrolled and randomly allocated to receive either YM (

Indexed as

MannansSleep QualityAdultDouble-Blind MethodHumansMiddle AgedPrebioticsSaccharomyces cerevisiaeSleepYoung AdultMannansPrebioticsfecal metabolomicsgut healthmannanprebioticsleepyeast

Identifiers

PMID38201970
PMCPMC10780920
OpenAlexW4390468489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.