Evidence map›Paper›PMID 38201958›Full record

Observational studyNutrients2023

Prolonged Fasting Induces Histological and Ultrastructural Changes in the Intestinal Mucosa That May Reduce Absorption and Revert after Enteral Refeeding.

Gonçalo Nunes, Marta Guimarães, Hélder Coelho, Ricardo Carregosa, Cátia Oliveira, Sofia S Pereira, António Alves de Matos, Jorge Fonseca

Registry-linked trialOpen access · goldAbstract readObservational Study
In one paragraph

Observational study in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07674589 (Combined Assessment of Gastrointestinal Hormones and Metabolomic Profiling Following Mixed-Meal Tolerance Tests in Patients at High Risk of Refeeding Syndrome), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07674589 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Combined Assessment of Gastrointestinal Hormones and Metabolomic Profiling Following Mixed-Meal Tolerance Tests in Patients at High Risk of Refeeding Syndrome: Study Protocol

TypeobservationalSponsorHospital Garcia de OrtaRan2026 to 2027Enrolled15ConditionsRefeeding Syndrome, Malnutrition
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Macronutrients as Regulators of Intestinal Epithelial Permeability: Where Do We Stand?Comprehensive reviews in food science and food safety · 2025
    Review
  8. EARLY REFEEDING AFTER COLORECTAL CANCER SURGERY REDUCES COMPLICATIONS AND LENGTH OF HOSPITAL STAY.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2025
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Gonçalo NunesGastroenterology Department, GENE-Artificial Feeding Team, Hospital Garcia de Orta, 2805-267 Almada, Portugal.ORCID 0000-0003-4920-9158
Marta GuimarãesUMIB-Unit for Multidisciplinary Research in Biomedicine, ICBAS-School of Medicine and Biomedical Sciences, Universidade do Porto, Rua Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.
Hélder CoelhoPathology Department, Hospital Garcia de Orta, 2805-267 Almada, Portugal.
Ricardo CarregosaCmicros-Centro de Microscopia Eletrónica e Histopatologia, CiiEM-Centro de Investigação Interdisciplinar Egas Moniz, 2829-511 Almada, Portugal.
Cátia OliveiraGastroenterology Department, GENE-Artificial Feeding Team, Hospital Garcia de Orta, 2805-267 Almada, Portugal.
Sofia S PereiraUMIB-Unit for Multidisciplinary Research in Biomedicine, ICBAS-School of Medicine and Biomedical Sciences, Universidade do Porto, Rua Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.ORCID 0000-0001-6947-4560
António Alves de MatosCmicros-Centro de Microscopia Eletrónica e Histopatologia, CiiEM-Centro de Investigação Interdisciplinar Egas Moniz, 2829-511 Almada, Portugal.
Jorge FonsecaGastroenterology Department, GENE-Artificial Feeding Team, Hospital Garcia de Orta, 2805-267 Almada, Portugal.ORCID 0000-0001-6477-7028
Universidade do Porto · PTHospital Garcia de Orta · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

FastingMalnutritionAdultDuodenumFemaleHumansIntestinal MucosaMaleProspective Studiesduodenal mucosahistologymalnutritionPEGultrastructure

Identifiers

PMID38201958
PMCPMC10780540
OpenAlexW4390468455

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.