Evidence map›Paper›PMID 38201941›Full record

ArticleNutrients2023

Intense Testing and Use of Vitamin D Supplements Leads to Slow Improvement in Vitamin D Adequacy Rates: A Cross-Sectional Analysis of Real-World Data.

Rodis D Paparodis, Dimitra Bantouna, Evangelos Karvounis, Ioannis Zoupas, Sarantis Livadas, Nicholas Angelopoulos, Shahnawaz Imam, Dimitrios T Papadimitriou, Juan C Jaume

Abstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rodis D PaparodisEndocrinology, Diabetes and Metabolism Clinics, Private Practice, 26221 Patras, Greece.ORCID 0000-0003-2804-0859
Dimitra BantounaHellenic Endocrine Network, 10682 Athens, Greece.
Evangelos KarvounisEndocrine Surgery Center of Excellence, Euroclinic Hospital, 11528 Athens, Greece.
Ioannis ZoupasSchool of Medicine, University of Athens, 11527 Athens, Greece.ORCID 0000-0003-4077-7407
Sarantis LivadasHellenic Endocrine Network, 10682 Athens, Greece.
Nicholas AngelopoulosHellenic Endocrine Network, 10682 Athens, Greece.ORCID 0000-0002-8901-7161
Shahnawaz ImamCenter for Diabetes and Endocrine Research, College of Medicine and Life Sciences, University of Toledo, Toledo, OH 43614, USA.ORCID 0000-0003-4700-5370
Dimitrios T PapadimitriouHellenic Endocrine Network, 10682 Athens, Greece.ORCID 0000-0002-6083-3560
Juan C JaumeDepartment of Medicine, Edward Hines, Jr. VA Hospital, Loyola University Chicago, Hines, IL 60141, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVitamin D testing (VDT) and supplement use (VDS) are on the rise, but most patients remain deficient (<30 ng/mL-VDD). We designed the present real-world study to assess this paradox.

methodsWe reviewed data from all patients visiting our clinics between 2014 and 2022. We estimated the rate of patients with vitamin D adequacy (≥30 ng/mL) (VDA) by year and month of testing, the dose of VDS (low (≤1200 IU/day), medium (1201-3000 I/day) and high dose (>3000 IU/day)), intake duration (short-term (<12 months) and long-term use (≥12 months)), and timing of use (current use, former use, no use).

resultsWe enrolled n = 6912 subjects with vitamin D measurements: n = 5195 females (75.2%), age 44.0 ± 16.8 years, BMI 27.9 ± 6.5 kg/m

conclusionsDespite the significant rise in VDT and VDS use, VDA was found in a minority of patients. Prolonged use of high-dose supplements produces modest improvements in VDA.

Indexed as

Vitamin DVitaminsAdultCluster AnalysisCross-Sectional StudiesDietary SupplementsFemaleHumansMaleMiddle AgedVitamin DVitaminscholecalciferolvitamin D adequacyvitamin D deficiencyvitamin D insufficiencyvitamin D supplementation

Identifiers

PMID38201941
PMCPMC10780961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.