Evidence map›Paper›PMID 38201730›Full record

ArticlePolymers2023

Elucidating the Role of Optical Activity of Polymers in Protein-Polymer Interactions.

Samin Jahan, Catherine Doyle, Anupama Ghimire, Diego Combita, Jan K Rainey, Brian D Wagner, Marya Ahmed

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Antifouling Coatings Inspired by Biological Templates.Macromolecular rapid communications · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Samin JahanDepartment of Chemistry, University of Prince Edward Island, Charlottetown, PE C1A 4P3, Canada.ORCID 0000-0001-8227-7895
Catherine DoyleDepartment of Chemistry, University of Prince Edward Island, Charlottetown, PE C1A 4P3, Canada.
Anupama GhimireDepartment of Biochemistry & Molecular Biology, Dalhousie University, Halifax, NS B3H 4R2, Canada.ORCID 0000-0003-2449-7405
Diego CombitaDepartment of Chemistry, University of Prince Edward Island, Charlottetown, PE C1A 4P3, Canada.
Jan K RaineyDepartment of Biochemistry & Molecular Biology, Dalhousie University, Halifax, NS B3H 4R2, Canada.ORCID 0000-0003-0793-5573
Brian D WagnerDepartment of Chemistry, University of Prince Edward Island, Charlottetown, PE C1A 4P3, Canada.ORCID 0000-0002-1951-0209
Marya AhmedDepartment of Chemistry, University of Prince Edward Island, Charlottetown, PE C1A 4P3, Canada.ORCID 0000-0003-4693-0724
University of Prince Edward Island · CADalhousie University · CA

Funding

Natural Sciences and Engineering Research Council RGPIN-2018-06183
6 · The paper itself

Abstract

Proteins are biomolecules with potential applications in agriculture, food sciences, pharmaceutics, biotechnology, and drug delivery. Interactions of hydrophilic and biocompatible polymers with proteins may impart proteolytic stability, improving the therapeutic effects of biomolecules and also acting as excipients for the prolonged storage of proteins under harsh conditions. The interactions of hydrophilic and stealth polymers such as poly(ethylene glycol), poly(trehalose), and zwitterionic polymers with various proteins are well studied. This study evaluates the molecular interactions of hydrophilic and optically active poly(vitamin B5 analogous methacrylamide) (poly(B5AMA)) with model proteins by fluorescence spectroscopy, nuclear magnetic resonance (NMR) spectroscopy, and circular dichroism (CD) spectroscopy analysis. The optically active hydrophilic polymers prepared using chiral monomers of

Indexed as

antifoulingchiral materialsprotein–polymer interactionsprotein stabilizing

Identifiers

PMID38201730
PMCPMC10781056
OpenAlexW4390176022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.