Evidence map›Paper›PMID 38201586›Full record

ArticleCancers2023

Cystoscopy Accuracy in Detecting Bladder Tumors: A Prospective Video-Confirmed Study.

Cathrine Silberg Guldhammer, Juan Luis Vásquez, Vibeke Møllegaard Kristensen, Thomas Norus, Naomi Nadler, Jørgen Bjerggaard Jensen, Nessn Azawi

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Cathrine Silberg GuldhammerDepartment of Urology, Zealand University Hospital, Sygehusvej 10, 4000 Roskilde, Denmark.ORCID 0009-0007-3810-0989
Juan Luis VásquezDepartment of Urology, Zealand University Hospital, Sygehusvej 10, 4000 Roskilde, Denmark.
Vibeke Møllegaard KristensenDepartment of Urology, Zealand University Hospital, Sygehusvej 10, 4000 Roskilde, Denmark.
Thomas NorusDepartment of Urology, Zealand University Hospital, Sygehusvej 10, 4000 Roskilde, Denmark.
Naomi NadlerDepartment of Urology, Zealand University Hospital, Sygehusvej 10, 4000 Roskilde, Denmark.
Jørgen Bjerggaard JensenDepartment of Urology, Arhus University Hospital, 8200 Aarhus, Denmark.ORCID 0000-0002-4347-739X
Nessn AzawiDepartment of Urology, Zealand University Hospital, Sygehusvej 10, 4000 Roskilde, Denmark.ORCID 0000-0001-7519-8654
University of Copenhagen · DKZealand University Hospital · DKAarhus University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBladder cancer ranks as the 10th most common cancer globally. The diagnosis of bladder tumors typically involves cystoscopy.

objectiveThis study aimed to evaluate the sensitivity and specificity of cystoscopy in detecting bladder tumors within a surveillance program following a bladder cancer diagnosis. DESIGN, SETTING, AND

participantsThis study utilized recordings of cystoscopies conducted at the Department of Urology, Zealand University Hospital, between July 2021 and November 2022. Clinical observations were cross-referenced with pathological results or follow-up cystoscopies. Clinically negative cystoscopies were further scrutinized for potential overlooked tumors. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Sensitivity and specificity of cystoscopy were assessed through ROC curve analysis. RESULTS AND LIMITATIONS: A total of 565 cystoscopies were recorded, with 135 indicating clinical positivity. Among 181 cystoscopies with clinically negative results that underwent a follow-up cystoscopy, 17 patients (9.4%) were subsequently diagnosed with bladder cancer, with the lesions identified in the initial cystoscopy. The sensitivity and specificity of cystoscopy in these cases were 81% and 73%, respectively.

conclusionThis trial underscores the underdiagnosis and undertreatment of bladder tumors within the current surveillance program. Additionally, aggressive malignant lesions may be overlooked, heightening the risk of disease progression. Therefore, it is recommended that cystoscopies be complemented by other diagnostic methods to ensure accurate diagnosis and proper patient treatment. PATIENT SUMMARY: This study involved 316 patients who underwent video-recorded cystoscopies and subsequent follow-up. Of these patients, 181 initially exhibited no clinical signs of bladder cancer. However, upon reviewing the recorded cystoscopy, bladder cancer was identified in 17 patients (9.4%).

Indexed as

aggressive malignant lesionsbladder cancercystoscopyoverdiagnosisovertreatmentsensitivityspecificitysupporting methodssurveillance programurine cytology

Identifiers

PMID38201586
PMCPMC10777997
OpenAlexW4390347747

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.