Evidence map›Paper›PMID 38201447›Full record

ArticleCancers2023

A Novel Method for Evaluating Early Tumor Response Based on Daily CBCT Images for Lung SBRT.

Wei Luo, Zijian Xiu, Xiaoqin Wang, Ronald McGarry, Joshua Allen

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Wei LuoDepartment of Radiation Medicine, University of Kentucky, 800 Rose Street, Lexington, KY 40536, USA.
Zijian XiuDepartment of Radiation Medicine, University of Kentucky, 800 Rose Street, Lexington, KY 40536, USA.
Xiaoqin WangDepartment of Radiology, University of Kentucky, 800 Rose Street, Lexington, KY 40536, USA.ORCID 0000-0003-4404-0082
Ronald McGarryDepartment of Radiation Medicine, University of Kentucky, 800 Rose Street, Lexington, KY 40536, USA.
Joshua AllenAdventHealth, 2501 N Orange Ave, Orlando, FL 32804, USA.
University of Kentucky · USAdventHealth Orlando · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to develop a new tumor response assessment method for lung SBRT.

methodsIn total, 132 lung cancer patients with 134 tumors who received SBRT treatment with daily CBCT were included in this study. The information about tumor size (area), contrast (contrast-to-noise ratio (CNR)), and density/attenuation (μ) was derived from the CBCT images for the first and the last fractions. The ratios of tumor area, CNR, and μ (R

resultsR ranged from 0.27 to 1.67 with a mean value of 0.95. Based on the radiologic assessment results, a receiver operation characteristic (ROC) curve with the area under the curve (AUC) of 95% was obtained and the optimal cutoff value (R

conclusionThe results show that R was correlated with early tumor response to lung SBRT and that using R for evaluating tumor response to SBRT would be viable and efficient.

Indexed as

cone-beam computerized tomography (CBCT)stereotactic radiation therapy (SBRT)tumor areatumor contrast-to-noise ratio (CNR)tumor linear attenuation coefficient (μ)tumor response assessment

Identifiers

PMID38201447
PMCPMC10778260
OpenAlexW4389977036

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.