Evidence map›Paper›PMID 38201414›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Retinal Disease Diagnosis Using Deep Learning on Ultra-Wide-Field Fundus Images.

Toan Duc Nguyen, Duc-Tai Le, Junghyun Bum, Seongho Kim, Su Jeong Song, Hyunseung Choo

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Toan Duc NguyenDepartment of AI Systems Engineering, Sungkyunkwan University, Suwon 16419, Republic of Korea.
Duc-Tai LeCollege of Computing and Informatics, Sungkyunkwan University, Suwon 16419, Republic of Korea.ORCID 0000-0002-5286-6629
Junghyun BumSungkyun AI Research Institute, Sungkyunkwan University, Suwon 16419, Republic of Korea.ORCID 0000-0002-9926-2910
Seongho KimDepartment of Ophthalmology, Kangbuk Samsung Hospital, School of Medicine, Sungkyunkwan University, Suwon 16419, Republic of Korea.
Su Jeong SongDepartment of Ophthalmology, Kangbuk Samsung Hospital, School of Medicine, Sungkyunkwan University, Suwon 16419, Republic of Korea.ORCID 0000-0003-2110-1874
Hyunseung ChooDepartment of AI Systems Engineering, Sungkyunkwan University, Suwon 16419, Republic of Korea.ORCID 0000-0002-6485-3155

Funding

Institute for Information & communication Technology Planning & evaluation, Artificial Intelligence Graduate School Program, Artificial Intelligence Innovation Hub, KBSMC-SKKU Future Clinical Convergence Academic Research Program IITP-2022-2020-0-0182, 2019-0-00421, 2021-0-02068
6 · The paper itself

Abstract

Ultra-wide-field fundus imaging (UFI) provides comprehensive visualization of crucial eye components, including the optic disk, fovea, and macula. This in-depth view facilitates doctors in accurately diagnosing diseases and recommending suitable treatments. This study investigated the application of various deep learning models for detecting eye diseases using UFI. We developed an automated system that processes and enhances a dataset of 4697 images. Our approach involves brightness and contrast enhancement, followed by applying feature extraction, data augmentation and image classification, integrated with convolutional neural networks. These networks utilize layer-wise feature extraction and transfer learning from pre-trained models to accurately represent and analyze medical images. Among the five evaluated models, including ResNet152, Vision Transformer, InceptionResNetV2, RegNet and ConVNext, ResNet152 is the most effective, achieving a testing area under the curve (AUC) score of 96.47% (with a 95% confidence interval (CI) of 0.931-0.974). Additionally, the paper presents visualizations of the model's predictions, including confidence scores and heatmaps that highlight the model's focal points-particularly where lesions due to damage are evident. By streamlining the diagnosis process and providing intricate prediction details without human intervention, our system serves as a pivotal tool for ophthalmologists. This research underscores the compatibility and potential of utilizing ultra-wide-field images in conjunction with deep learning.

Indexed as

convolutional neural networkdeep learningfundus imagemedical image processingvision transformer

Identifiers

PMID38201414
PMCPMC10804390

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.