Evidence map›Paper›PMID 38201413›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Radiological Features of Male Breast Neoplasms: How to Improve the Management of a Rare Disease.

Luca Nicosia, Luciano Mariano, Anna Carla Bozzini, Filippo Pesapane, Vincenzo Bagnardi, Samuele Frassoni, Chiara Oriecuia, Valeria Dominelli, Antuono Latronico, Simone Palma and 6 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 1 country.

Luca NicosiaBreast Imaging Division, Radiology Department, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0003-3979-8075
Luciano MarianoBreast Imaging Division, Radiology Department, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.
Anna Carla BozziniBreast Imaging Division, Radiology Department, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.
Filippo PesapaneBreast Imaging Division, Radiology Department, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0002-0374-5054
Vincenzo BagnardiDepartment of Statistics and Quantitative Methods, University of Milan-Bicocca, 20126 Milan, Italy.
Samuele FrassoniDepartment of Statistics and Quantitative Methods, University of Milan-Bicocca, 20126 Milan, Italy.ORCID 0000-0002-4265-2627
Chiara OriecuiaDepartment of Clinical and Experimental Sciences, University of Brescia, 25121 Brescia, Italy.ORCID 0000-0002-0079-6446
Valeria DominelliBreast Imaging Division, Radiology Department, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.
Antuono LatronicoBreast Imaging Division, Radiology Department, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.
Simone PalmaDepartment of Bioimaging, Radiation Oncology and Hematology, UOC of Radiologia, Fondazione Policlinico Universitario A. Gemelli IRCSS, Largo A. Gemelli 8, 00168 Rome, Italy.ORCID 0000-0002-8824-2535
Massimo VenturiniDepartment of Diagnostic and Interventional Radiology, University of Insubria, Ospedale di Circolo e Fondazione Macchi, 21100 Varese, Italy.
Federico FontanaDepartment of Diagnostic and Interventional Radiology, University of Insubria, Ospedale di Circolo e Fondazione Macchi, 21100 Varese, Italy.ORCID 0000-0002-3809-5696
Francesca PrioloBreast Imaging Division, Radiology Department, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.
Ida AbiusoRadiology Department, Università degli Studi di Torino, 10129 Turin, Italy.
Claudia SangalliData Management, European Institute of Oncology IRCCS, 20141 Milan, Italy.
Enrico CassanoBreast Imaging Division, Radiology Department, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0002-3437-8939
European Institute of Oncology · ITUniversity of Insubria · ITUniversity of Milano-Bicocca · ITAgostino Gemelli University Polyclinic · ITData Management (Italy) · ITUniversity of Brescia · ITUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The primary aim of our study was to assess the main mammographic and ultrasonographic features of invasive male breast malignancies. The secondary aim was to evaluate whether a specific radiological presentation would be associated with a worse receptor profile. Radiological images (mammography and/or ultrasound) of all patients who underwent surgery for male invasive breast cancer in our institution between 2008 and 2023 were retrospectively analyzed by two breast radiologists in consensus. All significant features of radiological presentation known in the literature were re-evaluated. Fifty-six patients were selected. The mean age at surgery of patients was 69 years (range: 35-81); in 82% of cases (46 patients), the histologic outcome was invasive ductal carcinoma. A total of 28 out of 56 (50%) patients had preoperative mammography; in 9/28 cases (32%), we found a mass with microcalcifications on mammography. The mass presented high density in 25 out of 28 patients (89%); the mass showed irregular margins in 15/28 (54%) cases. A total of 46 out of 56 patients had preoperative ultrasounds. The lesion showed a solid mass in 41/46 (89%) cases. In 5/46 patients (11%), the lesion was a mass with a mixed (partly liquid-partly solid) structure. We did not find any statistically significant correlation between major types of radiological presentation and tumor receptor arrangement. Knowledge of the main radiologic presentation patterns of malignant male breast neoplasm can help better manage this type of disease, which is rare but whose incidence is increasing.

Indexed as

breast ultrasoundmale breast cancermammography

Identifiers

PMID38201413
PMCPMC10795707
OpenAlexW4390538707

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.