Evidence map›Paper›PMID 38201285›Full record

ArticleCells2023

Characterization of a Preclinical In Vitro Model Derived from a SMARCA4-Mutated Sinonasal Teratocarcinosarcoma.

Sara Lucila Lorenzo-Guerra, Helena Codina-Martínez, Laura Suárez-Fernández, Virginia N Cabal, Rocío García-Marín, Cristina Riobello, Blanca Vivanco, Verónica Blanco-Lorenzo, Paula Sánchez-Fernández, Fernando López and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Sinonasal Teratocarcinosarcoma in a Thirty Five Year Old Male Patient: A Case Report from a Regional Cancer Institute of Eastern India.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
  4. Epigenetics-targeted drugs: current paradigms and future challenges.Signal transduction and targeted therapy · 2024
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Sara Lucila Lorenzo-GuerraDepartment of Head and Neck Cancer, Health Research Institute of the Principality of Asturias, 33011 Oviedo, Spain.ORCID 0000-0002-9169-0267
Helena Codina-MartínezDepartment of Head and Neck Cancer, Health Research Institute of the Principality of Asturias, 33011 Oviedo, Spain.ORCID 0000-0003-3895-8655
Laura Suárez-FernándezDepartment of Head and Neck Cancer, Health Research Institute of the Principality of Asturias, 33011 Oviedo, Spain.ORCID 0009-0004-0835-7546
Virginia N CabalDepartment of Head and Neck Cancer, Health Research Institute of the Principality of Asturias, 33011 Oviedo, Spain.ORCID 0000-0002-4490-5747
Rocío García-MarínDepartment of Head and Neck Cancer, Health Research Institute of the Principality of Asturias, 33011 Oviedo, Spain.ORCID 0000-0003-0331-2002
Cristina RiobelloDepartment of Head and Neck Cancer, Health Research Institute of the Principality of Asturias, 33011 Oviedo, Spain.ORCID 0000-0002-8854-6854
Blanca VivancoDepartment of Pathology, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.
Verónica Blanco-LorenzoDepartment of Pathology, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.
Paula Sánchez-FernándezDepartment of Otolaryngology, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.
Fernando LópezDepartment of Otolaryngology, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.ORCID 0000-0001-7019-9746
Jóse Luis LlorenteDepartment of Otolaryngology, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.
Mario A HermsenDepartment of Head and Neck Cancer, Health Research Institute of the Principality of Asturias, 33011 Oviedo, Spain.ORCID 0000-0002-5959-6289
Gobierno del Principado de Asturias · ESHospital Universitario Central de Asturias · ES

Funding

Centro de Investigación Biomédica en Red de Cáncer CB16/12/00390Gobierno del Principado de Asturias IDI2018/155Instituto de Salud Carlos III FI20/00137Instituto de Salud Carlos III PI19/00191Instituto de Salud Carlos III PI20/00383Instituto de Salud Carlos III PI22/00506
6 · The paper itself

Abstract

Sinonasal teratocarcinosarcoma (TCS) is a rare tumor that displays a variable histology with admixtures of epithelial, mesenchymal, neuroendocrine and germ cell elements. Facing a very poor prognosis, patients with TCS are in need of new options for treatment. Recently identified recurrent mutations in

Indexed as

CarcinosarcomaNose NeoplasmsSarcomaTeratomaCyclin-Dependent Kinase Inhibitor ProteinsDNA HelicasesHumansNuclear ProteinsTranscription FactorsCyclin-Dependent Kinase Inhibitor ProteinsDNA HelicasesNuclear ProteinsSMARCA4 protein, humanTranscription Factorsexome sequencingin vitro modelpreclinical drug testingsinonasal cancerSMARCA4 mutationteratocarcinosarcoma

Identifiers

PMID38201285
PMCPMC10778008
OpenAlexW4390459477

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.