Evidence map›Paper›PMID 38200798›Full record

ArticleAnimals : an open access journal from MDPI2023

Chronic Inflammatory Enteropathy and Low-Grade Intestinal T-Cell Lymphoma Are Associated with Altered Microbial Tryptophan Catabolism in Cats.

Patrick C Barko, David A Williams, Yu-An Wu, Joerg M Steiner, Jan S Suchodolski, Arnon Gal, Sina Marsilio

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Patrick C BarkoDepartments of Veterinary Clinical Medicine and Pathobiology, University of Illinois at Urbana-Champaign, Urbana, IL 61802, USA.ORCID 0000-0003-1156-7427
David A WilliamsDepartments of Veterinary Clinical Medicine and Pathobiology, University of Illinois at Urbana-Champaign, Urbana, IL 61802, USA.
Yu-An WuGastrointestinal Laboratory, School of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
Joerg M SteinerGastrointestinal Laboratory, School of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
Jan S SuchodolskiGastrointestinal Laboratory, School of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
Arnon GalDepartment of Veterinary Clinical Medicine, University of Illinois at Urbana-Champaign, Urbana, IL 61802, USA.ORCID 0000-0002-6449-2812
Sina MarsilioDepartment of Veterinary Medicine and Epidemiology, UC Davis School of Veterinary Medicine, Davis, CA 95616, USA.ORCID 0000-0002-0693-0669
Texas A&M University · USUniversity of Illinois Urbana-Champaign · USUniversity of California, Davis · US

Funding

Every Cat Health Foundation Miller Trust Grant MT21-003
6 · The paper itself

Abstract

Chronic inflammatory enteropathy (CIE) and low-grade intestinal T-cell lymphoma (LGITL) are common chronic enteropathies (CE) in cats. Enteric microbiota dysbiosis is implicated in the pathogenesis of CE; however, the mechanisms of host-microbiome interactions are poorly understood in cats. Microbial indole catabolites of tryptophan (MICT) are gut bacterial catabolites of tryptophan that are hypothesized to regulate intestinal inflammation and mucosal barrier function. MICTs are decreased in the sera of humans with inflammatory bowel disease and previous studies identified altered tryptophan metabolism in cats with CE. We sought to determine whether MICTs were decreased in cats with CE using archived serum samples from cats with CIE (

Indexed as

alimentary small cell lymphomachronic enteropathyindoleinflammatory bowel diseasemicrobial indole catabolites of tryptophan

Identifiers

PMID38200798
PMCPMC10777963
OpenAlexW4390174917

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.