Evidence map›Paper›PMID 38200447›Full record

ArticleBMC medical imaging2024

T1 mapping as a quantitative imaging biomarker for diagnosing cervical cancer: a comparison with diffusion kurtosis imaging.

Zanxia Zhang, Jie Liu, Yong Zhang, Feifei Qu, Robert Grimm, Jingliang Cheng, Weijian Wang, Jinxia Zhu, Shujian Li

Open access · goldAbstract read
In one paragraph

Article in BMC medical imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
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  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Zanxia Zhang *Department of MRI, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe Dong Road, 450052, Zhengzhou, Henan, China.
Jie Liu *Department of MRI, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe Dong Road, 450052, Zhengzhou, Henan, China.
Yong ZhangDepartment of MRI, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe Dong Road, 450052, Zhengzhou, Henan, China.
Feifei QuMR Collaboration, Siemens Healthcare Ltd, Beijing, China.
Robert GrimmMR Application, Siemens Healthcare GmbH, Predevelopment, Erlangen, Germany.
Jingliang ChengDepartment of MRI, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe Dong Road, 450052, Zhengzhou, Henan, China.
Weijian WangDepartment of MRI, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe Dong Road, 450052, Zhengzhou, Henan, China.
Jinxia ZhuMR Collaboration, Siemens Healthcare Ltd, Beijing, China.
Shujian LiDepartment of MRI, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe Dong Road, 450052, Zhengzhou, Henan, China. zzhsj2008@163.com.
First Affiliated Hospital of Zhengzhou University · CNSiemens (China) · CNSiemens Healthcare (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundT1 mapping can potentially quantitatively assess the intrinsic properties of tumors. This study was conducted to explore the ability of T1 mapping in distinguishing cervical cancer type, grade, and stage and compare the diagnostic performance of T1 mapping with diffusion kurtosis imaging (DKI).

methodsOne hundred fifty-seven patients with pathologically confirmed cervical cancer were enrolled in this prospectively study. T1 mapping and DKI were performed. The native T1, difference between native and postcontrast T1 (T1diff), mean kurtosis (MK), mean diffusivity (MD), and apparent diffusion coefficient (ADC) were calculated. Cervical squamous cell carcinoma (CSCC) and adenocarcinoma (CAC), low- and high-grade carcinomas, and early- and advanced-stage groups were compared using area under the receiver operating characteristic (AUROC) curves.

resultsThe native T1 and MK were higher, and the MD and ADC were lower for CSCC than for CAC (all p < 0.05). Compared with low-grade CSCC, high-grade CSCC had decreased T1

conclusionsCompared with DKI-derived parameters, native T1 exhibits better efficacy for identifying cervical cancer subtype and stage, and T1

Indexed as

AdenocarcinomaCarcinoma, Squamous CellUterine Cervical NeoplasmsBiomarkersDiffusion Tensor ImagingFemaleHumansBiomarkersCervical cancerDiffusion kurtosis imagingMagnetic resonance imagingT1 mapping

Identifiers

PMID38200447
PMCPMC10782683
OpenAlexW4390694664

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.