Evidence map›Paper›PMID 38200328›Full record

SynthesisEvidence-based dentistry2024

The role of calcium in the prevention of erosive tooth wear: a systematic review and meta-analysis.

Konstantina Chatzidimitriou, Kyriaki Seremidi, Dimitrios Kloukos, Sotiria Gizani, William Papaioannou

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Evidence-based dentistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Konstantina ChatzidimitriouDepartment of Preventive & Community Dentistry, National and Kapodistrian University of Athens, School of Dentistry, 2 Thivon Str, 115 27, Goudi, Athens, Greece. konchatzid@dent.uoa.gr.
Kyriaki SeremidiDepartment of Paediatric Dentistry, National and Kapodistrian University of Athens, School of Dentistry, 2 Thivon Str, 115 27, Goudi, Athens, Greece.
Dimitrios KloukosDepartment of Orthodontics and Dentofacial Orthopedics, University of Bern, CH-3012, Hochschulstrasse 4, Bern, Switzerland.
Sotiria GizaniDepartment of Paediatric Dentistry, National and Kapodistrian University of Athens, School of Dentistry, 2 Thivon Str, 115 27, Goudi, Athens, Greece.
William PapaioannouDepartment of Preventive & Community Dentistry, National and Kapodistrian University of Athens, School of Dentistry, 2 Thivon Str, 115 27, Goudi, Athens, Greece.
National and Kapodistrian University of Athens · GRUniversity of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe loss of hard dental tissue due to recurrent acid challenges and mechanical stresses without bacterial involvement is known as erosive tooth wear (ETW). Many studies in the literature have concentrated on variables that may affect the ETW process and prevent its occurrence or reduce its advancement. However, to date, no previous systematic review has evaluated the role of calcium in preventing ETW. Therefore, the purpose of the present systematic review was to review and critically appraise the scientific evidence regarding the role of calcium formulations in the prevention of ETW.

methodsThe review protocol was registered in the PROSPERO international prospective register of systematic reviews (Ref: CRD42021229819). A literature search was conducted in electronic databases to identify in situ randomized controlled trials evaluating the prevention of ETW following the application of calcium formulations. The outcomes studied included mean enamel loss, surface microhardness, surface roughness, mean erosion/softening depth, mineral loss/precipitation and remineralization. Study characteristics and outcomes of included studies were summarized. Cochrane's risk-of-bias tool 2.0 was used to assess the quality of eligible studies, and meta-analysis using a random effects model was performed.

resultsThe search retrieved 869 studies of which 21 were considered eligible. Regarding the results of the quality assessment for potential risk of bias in all included studies, overall, 5 studies were considered as being at low risk, another 12 at unclear risk and 4 at high risk of bias. The findings of the studies showed that the addition of calcium in juice drinks led to reduced enamel loss, with blackcurrant juice presenting 2.6 times statistically significant less enamel loss compared to orange juice (p = 0.0001, I

conclusionsCalcium formulations play an important role in ETW prevention, mainly through their addition to acidic drinks.

Indexed as

Tooth ErosionCalciumDental EnamelHumansTooth WearCalcium

Identifiers

PMID38200328
OpenAlexW4390702196

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.