ArticleNature2024
The selection landscape and genetic legacy of ancient Eurasians.
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Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.
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68citing papers in PubMed
66.0field-weighted citation impact, top 1% of its field
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Who cites it
68 citing papers in PubMed, 124 citations in OpenAlex.
- Ancient DNA and Human Physiology.Physiology (Bethesda, Md.) · 2026Review
- Western Hunter-Gatherer genetic ancestry contributes to human longevity in the Italian population.GeroScience · 2026Article
- Genomic insights into natural selection in recent human history.Nature reviews. Genetics · 2026Review
- Genetic trade-offs in fertility and longevity explain the maintenance of disease-associated alleles in humans.Nature ecology & evolution · 2026Article
- Local ancestry inference identifies robust evidence of selection in Neolithic Europe.Molecular biology and evolution · 2026Article
- High-coverage paleo-genome research identifies a pathogenic mutation on EXT1 in a Qing-period Chinese individual with multiple osteochondromas.Molecular genetics and genomics : MGG · 2026Article
- Layers in the sand: The genetic imprint of migration, culture, and Indus craft in the Thar Desert.HGG advances · 2026Article
- The Tianshan Mountains as a biogeographic barrier driving North-South divergence and local adaptation inPlant diversity · 2026Article
- Selection-guided discovery in South Asians implicates the MAPT locus in insulin resistance.medRxiv : the preprint server for health sciences · 2026Article
- Targeting Zoonotic Spillover Drivers for Global Pandemic Prevention: A Narrative Review.Microorganisms · 2026Review
- Article
- Fast pairwise coalescence enables gene-resolution scans for recent selection in diverse human populations.bioRxiv : the preprint server for biology · 2026Article
- Recurrent structural variation and recent turnover at the 17q21.31 locus in humans and great apes.Nature communications · 2026Article
- Using drift coefficients as a basis for inferring times, effective population sizes, and genetic adaptations.Molecular biology and evolution · 2026Article
- Insights into human adaptation from ancient DNA.Nature genetics · 2026Review
- Insights into infectious diseases through ancient pathogen genomics.Nature reviews. Microbiology · 2026Review
- The persistence and loss of hard selective sweeps amid admixture in ancient Eurasians.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Optimal Reference Panel Design in Ancient DNA Imputation from Coalescent Theory, Simulation, and Real Data Application with an Ancient Reference Panel.bioRxiv : the preprint server for biology · 2026Article
- Ancient DNA reveals that natural selection has upregulated the immune system over the last 10,000 years.bioRxiv : the preprint server for biology · 2026Article
- Temporal shifts in polygenic traits track major epidemics in Western Eurasia.bioRxiv : the preprint server for biology · 2026Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
34 authors at 11 institutions in 7 countries.
Evan K Irving-Pease *Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark. evan.irvingpease@gmail.com.ORCID 0000-0003-1940-2192
Alba Refoyo-Martínez *Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
William Barrie *GeoGenetics Group, Department of Zoology, University of Cambridge, Cambridge, UK.
Andrés Ingason *Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
Alice Pearson *Department of Genetics, University of Cambridge, Cambridge, UK.
Anders Fischer *Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-0852-5904
Karl-Göran SjögrenDepartment of Historical Studies, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0003-1791-3175
Alma S HalgrenDepartment of Integrative Biology, University of California Berkeley, Berkeley, CA, USA.ORCID 0000-0002-7112-5930
Ruairidh MacleodGeoGenetics Group, Department of Zoology, University of Cambridge, Cambridge, UK.ORCID 0000-0001-8086-4420
Fabrice DemeterLundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
Rasmus A HenriksenLundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-3657-1983
Tharsika VimalaLundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
Hugh McCollLundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-7568-4270
Andrew H VaughnCenter for Computational Biology, University of California, Berkeley, CA, USA.
Leo SpeidelUCL Genetics Institute, University College London, London, UK.
Aaron J SternCenter for Computational Biology, University of California, Berkeley, CA, USA.
Gabriele ScorranoLundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-0887-4023
Abigail RamsøeLundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
Andrew J SchorkInstitute of Biological Psychiatry, Mental Health Services, Copenhagen University Hospital, Roskilde, Denmark.
Anders RosengrenLundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-6682-1288
Lei ZhaoLundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-6551-2707
Kristian KristiansenLundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
Astrid K N IversenOxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK.ORCID 0000-0002-3507-5956
Lars FuggerOxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK.ORCID 0000-0003-2883-3226
Peter H SudmantDepartment of Integrative Biology, University of California Berkeley, Berkeley, CA, USA.ORCID 0000-0002-9573-8248
Daniel J LawsonInstitute of Statistical Sciences, School of Mathematics, University of Bristol, Bristol, UK.ORCID 0000-0002-5311-6213
Richard DurbinDepartment of Genetics, University of Cambridge, Cambridge, UK.ORCID 0000-0002-9130-1006
Thorfinn KorneliussenLundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-7576-5380
Thomas WergeLundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-1829-0766
Morten E AllentoftLundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-4424-3568
Martin SikoraLundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-2818-8319
Rasmus NielsenLundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark. rasmus_nielsen@berkeley.edu.ORCID 0000-0003-0513-6591
Fernando RacimoLundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark. fracimo@sund.ku.dk.ORCID 0000-0002-5025-2607
Eske WillerslevLundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark. ew482@cam.ac.uk.ORCID 0000-0002-7081-6748
University of Copenhagen · DKUniversity of California, Berkeley · USUniversity of Cambridge · GBAarhus University Hospital · DKBerkeley College · USJohn Radcliffe Hospital · GBThe Francis Crick Institute · GBTranslational Genomics Research Institute · USUniversity of Bremen · DEUniversity of Bristol · GBUniversity of Gothenburg · SE
Funding
The evolution and diversity of mutation, molecular fidelity, and genome structureR35GM142916 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Peter Heshedahl Sudmant · 2021 to 2026
$2.5MEnabling Precision Genomics Using Adaptive VariationR01GM138634 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI NIELSEN, RASMUS · 2020 to 2023
$1.7MNIGMS NIH HHS R01 GM138634NIGMS NIH HHS R35 GM142916Wellcome Trust 207492/Z/17/Z
Abstract
The Holocene (beginning around 12,000 years ago) encompassed some of the most significant changes in human evolution, with far-reaching consequences for the dietary, physical and mental health of present-day populations. Using a dataset of more than 1,600 imputed ancient genomes
Indexed as
AsianEuropean PeopleGenome, HumanSelection, GeneticAffectAgricultureAllelesAlzheimer DiseaseAsiaDiabetes MellitusEuropeFarmersGenetic LociGenetic Predisposition to DiseaseHistory, AncientHuman Migration
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