Evidence map›Paper›PMID 38199850›Full record

ArticleRMD open2024

Atlas for the CT Syndesmophyte Score (CTSS) in patients with axial spondyloarthritis.

Mary Lucy Marques, Sofia Ramiro, Désirée van der Heijde, Monique Reijnierse, Torsten Diekhoff, Kay Geert A Hermann, Floris A van Gaalen, Manouk de Hooge

Open access · goldAbstract read
In one paragraph

Article in RMD open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Advances in cartilage imaging techniques.Nature reviews. Rheumatology · 2026
    Review
  2. Axial Imaging in Spondyloarthritis.Rheumatic diseases clinics of North America · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 4 countries.

Mary Lucy MarquesDepartment of Rheumatology, Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands mary.lucy.marques@gmail.com.ORCID 0000-0002-3071-9425
Sofia RamiroDepartment of Rheumatology, Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands.ORCID 0000-0002-8899-9087
Désirée van der HeijdeDepartment of Rheumatology, Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands.ORCID 0000-0002-5781-158X
Monique ReijnierseDepartment of Radiology, Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands.ORCID 0000-0002-6906-1851
Torsten DiekhoffDepartment of Radiology, Charité Universitätsmedizin Berlin, Berlin, Berlin, Germany.ORCID 0000-0003-3593-1449
Kay Geert A HermannDepartment of Radiology, Charité Universitätsmedizin Berlin, Berlin, Berlin, Germany.ORCID 0000-0001-6142-3814
Floris A van GaalenDepartment of Rheumatology, Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands.ORCID 0000-0001-8448-7407
Manouk de HoogeDepartment of Rheumatology, University Hospital Ghent, Gent, Oost-Vlaanderen, Belgium.ORCID 0000-0002-0652-9808
Leiden University Medical Center · NLCharité - Universitätsmedizin Berlin · DEGhent University Hospital · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Computed Tomography Syndesmophyte Score (CTSS) was developed as a reliable and sensitive tool to assess syndesmophytes in low-dose CT images of the entire spine in patients with axial spondyloarthritis (axSpA). The original paper provided sparce examples of the CTSS grades.

objectivesProvide an atlas tailored to assist readers in understanding and employing the CTSS method.

methodsIn this paper, illustrations of the different grades and views of the CTSS are presented. CTSS is used to measure bone formation in the spine of patients with axial spondyloarthritis (axSpA), in the form of syndesmophytes. In both the sagittal and coronal planes, syndesmophytes can be graded from 0 to 3 over 23 vertebral units starting at C2 and ending at S1. The CTSS ranges from 0 (absence of axSpA-related syndesmophytes) to 552 (total ankylosis of the spine).

resultsThe current atlas contains low-dose CT images of the spine without lesions (for reference) and all grades of syndesmophytes in different planes used in the CTSS. Examples are arranged per spinal segment (cervical, thoracic and lumbar).

conclusionsThese images can be used to assist any reader in the assessment of syndesmophytes on (low-dose) CT in patients with axSpA.

Indexed as

Axial SpondyloarthritisHumansOsteogenesisSpineTomography, X-Ray ComputedOutcome Assessment, Health CareSpondylitis, AnkylosingSpondyloarthritis

Identifiers

PMID38199850
PMCPMC10806465
OpenAlexW4390719388

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.