Evidence map›Paper›PMID 38199272›Full record

ArticleNeurobiology of disease2024

Synaptic Zn

Michael C Bennett, Katelyn M Reinhart, Jordan E Weisend, Russell A Morton, Andrew P Carlson, C William Shuttleworth

Open access · goldAbstract read
In one paragraph

Article in Neurobiology of disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Michael C BennettDepartment of Neurosciences, University of New Mexico School of Medicine, Albuquerque, NM, USA.
Katelyn M ReinhartDepartment of Neurosciences, University of New Mexico School of Medicine, Albuquerque, NM, USA.
Jordan E WeisendDepartment of Neurosciences, University of New Mexico School of Medicine, Albuquerque, NM, USA.
Russell A MortonDepartment of Neurosciences, University of New Mexico School of Medicine, Albuquerque, NM, USA.
Andrew P CarlsonDepartment of Neurosurgery, University of New Mexico School of Medicine, Albuquerque, NM, USA.
C William ShuttleworthDepartment of Neurosciences, University of New Mexico School of Medicine, Albuquerque, NM, USA. Electronic address: bshuttleworth@salud.unm.edu.
University of New Mexico · US

Funding

University of New Mexico (UNM) Center for Brain Recovery and RepairP20GM109089 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI CUNNINGHAM, LEE ANNA · 2015 to 2024
$22.7M
MINORITY INSTITUTIONAL RESEARCH TRAINING PROGRAM (T32)T32HL007736 · NHLBI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI RESTA, THOMAS C · 1993 to 2025
$6.5M
Spreading Depolarizations and Neuronal VulnerabilityR01NS106901 · NINDS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Claude W Shuttleworth · 2018 to 2026
$2.5M
Non-canonical mechanisms of excitotoxicityF31NS129351 · NINDS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI BENNETT, MICHAEL · 2023 to 2024
$81k
NHLBI NIH HHS T32 HL007736NIGMS NIH HHS P20 GM109089NINDS NIH HHS F31 NS129351NINDS NIH HHS R01 NS106901
6 · The paper itself

Abstract

Spreading depolarizations (SDs) are profound waves of neuroglial depolarization that can propagate repetitively through injured brain. Recent clinical work has established SD as an important contributor to expansion of acute brain injuries and have begun to extend SD studies into other neurological disorders. A critical challenge is to determine how to selectively prevent deleterious consequences of SD. In the present study, we determined whether a wave of profound Zn

Indexed as

Cortical Spreading DepressionHippocampusAnimalsChelating AgentsMembrane Transport ProteinsMiceNeurogliaZincChelating AgentsMembrane Transport ProteinsZinchippocampusIschemiaSpreading depressionZincZnT3

Identifiers

PMID38199272
PMCPMC10869643
OpenAlexW4390686430

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.