Evidence map›Paper›PMID 38198298›Full record

ArticleRevista da Associacao Medica Brasileira (1992)2024

Log odds of positive nodes as a prognostic factor for rectal cancer: a retrospective study.

Aydin Yavuz, Cagri Buyukkasap, Saygin Altiner, Berra Kurtoglu, Can Koyuncuoglu, Huseyin Gobut, Kursat Dikmen, Hasan Bostanci, Osman Yuksel

Open access · diamondAbstract read
In one paragraph

Article in Revista da Associacao Medica Brasileira (1992), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 100% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Aydin YavuzGazi University, Faculty of Medicine, Department of General Surgery - Ankara, Turkey.ORCID http://orcid.org/0000-0003-0091-7997
Cagri BuyukkasapGazi University, Faculty of Medicine, Department of General Surgery - Ankara, Turkey.ORCID http://orcid.org/0000-0002-9141-4289
Saygin AltinerAnkara Training and Research Hospital, Department of General Surgery - Ankara, Turkey.ORCID http://orcid.org/0000-0001-6118-9984
Berra KurtogluGazi University, Faculty of Medicine - Ankara, Turkey.ORCID http://orcid.org/0000-0002-9085-7563
Can KoyuncuogluGazi University, Faculty of Medicine, Department of General Surgery - Ankara, Turkey.ORCID http://orcid.org/0000-0001-5448-2242
Huseyin GobutGazi University, Faculty of Medicine, Department of General Surgery - Ankara, Turkey.ORCID http://orcid.org/0000-0003-0127-7039
Kursat DikmenGazi University, Faculty of Medicine, Department of General Surgery - Ankara, Turkey.ORCID http://orcid.org/0000-0002-9150-9499
Hasan BostanciGazi University, Faculty of Medicine, Department of General Surgery - Ankara, Turkey.ORCID http://orcid.org/0000-0002-3160-1488
Osman YukselGazi University, Faculty of Medicine, Department of General Surgery - Ankara, Turkey.ORCID http://orcid.org/0000-0003-4784-908X
Gazi Hastanesi · TRMinistry of Health · TRUniversity of Lagos · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveRectal cancer is an important cause of mortality and morbidity globally. The aim of this study was to investigate whether the log odds of positive nodes system is a better indicator than tumor node metastasis and lymph node ratio systems to determine rectum cancer prognosis, which is an important cause of mortality and morbidity globally.

methodsThis was a single-center retrospective cross-sectional study. Data were obtained from the medical records of patients with rectum adenocarcinoma followed at Gazi University Hospital. The clinicopathological data of 128 patients with rectum adenocarcinoma who underwent low anterior resection or abdominoperineal resection between January 2010 and December 2018 was retrospectively reviewed. Patients with rectum adenocarcinoma as the first and only primary diagnosis, which was confirmed by histopathological examination, than those who had undergone complete curative resection via low anterior resection or abdominoperineal resection were included. Those with familial adenomatous polyposis or Lynch syndrome, those under 18 years of age, with a synchronous tumor, peritoneal spread, or metastatic disease at the time of diagnosis, and those with <12 lymph nodes dissected from the resection material were excluded from the study.

resultsIn multivariate analysis, age, perineural invasion, tumor node metastasis stage, lymph node ratio stage, and log odds of positive nodes stage were found to be independent prognostic factors (p<0.05). LODDS2 patients' mortality rates were 9.495 times higher than LODDS0 patients [hazard ratio=9.495, (95%CI 4.155-21.694), p<0.001] while LNR2 stage patients' mortality rates were 7.016 times higher than LNR0 stage patients [hazard ratio=7.016, (95%CI 3.123-15.765), p<0.001] and N2 stage patients had a 5.135 times higher risk of mortality than those who were in N0 stage [hazard ratio=5.135 (95%CI 2.451-10.756), p<0.001].

conclusionLog odds of positive nodes is a more valuable prognostic factor for rectal cancer patients than tumor node metastasis and lymph node ratio systems to determine rectum cancer prognosis.

Indexed as

AdenocarcinomaRectal NeoplasmsAdolescentCross-Sectional StudiesHumansPrognosisRetrospective Studies

Identifiers

PMID38198298
PMCPMC10768676
OpenAlexW4390603778

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.