Evidence map›Paper›PMID 38197635›Full record

ArticleJournal of bacteriology2024

Binding of GTP to BifA is required for the production of Pel-dependent biofilms in

Jaime C Van Loon, Gregory B Whitfield, Nicole Wong, Lindsey O'Neal, Amy Henrickson, Borries Demeler, G A O'Toole, Matthew R Parsek, P Lynne Howell

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bacteriology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Jaime C Van LoonProgram in Molecular Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID 0000-0001-8714-2922
Gregory B WhitfieldProgram in Molecular Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.
Nicole WongProgram in Molecular Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.
Lindsey O'NealDepartment of Microbiology, University of Washington, Seattle, Washington, USA.
Amy HenricksonDepartment of Chemistry and Biochemistry, University of Lethbridge, Lethbridge, Alberta, Canada.
Borries DemelerDepartment of Chemistry and Biochemistry, University of Lethbridge, Lethbridge, Alberta, Canada.
G A O'TooleDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.ORCID 0000-0002-2861-4392
Matthew R ParsekDepartment of Microbiology, University of Washington, Seattle, Washington, USA.
P Lynne HowellProgram in Molecular Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID 0000-0002-2776-062X
University of Toronto · CAUniversity of Lethbridge · CAUniversity of Washington · USDartmouth College · USHospital for Sick Children · CA

Funding

The pel exopolysaccharide gene cluster of Pseudomonas aeruginosaR01AI077628 · NIAID · UNIVERSITY OF WASHINGTON · PI MATTHEW R. PARSEK, Daniel J Wozniak · 2009 to 2026
$7.1M
cdiGMP regulation of Biofilm FormationR37AI083256 · NIAID · DARTMOUTH COLLEGE · PI O'TOOLE, GEORGE A. · 2014 to 2023
$4.7M
Development of an UltraScan Meta-Scheduler for HPC Job SubmissionR01GM120600 · NIGMS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Emre H. Brookes, BORRIES DEMELER · 2016 to 2026
$3.6M
The biofilm matrix of P. aeruginosaR01AI143916 · NIAID · UNIVERSITY OF WASHINGTON · PI MACCOSS, MICHAEL, PARSEK, MATTHEW R. · 2019 to 2023
$2.9M
NIAID NIH HHS R01 AI077628NIAID NIH HHS R01 AI143916NIAID NIH HHS R37 AI083256NIGMS NIH HHS R01 GM120600
6 · The paper itself

Abstract

The Pel exopolysaccharide is one of the most mechanistically conserved and phylogenetically diverse bacterial biofilm matrix determinants. Pel is a major contributor to the structural integrity of

Indexed as

Escherichia coli ProteinsPseudomonas aeruginosaBacterial ProteinsBiofilmsCyclic GMPGene Expression Regulation, BacterialGuanosine TriphosphatePhosphoric Diester HydrolasesBacterial ProteinsCyclic GMPEscherichia coli ProteinsGuanosine TriphosphatePhosphoric Diester Hydrolasesc-di-GMPGTPphosphodiesterasePseudomonasregulation

Identifiers

PMID38197635
PMCPMC10882990
OpenAlexW4390703518

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.