Evidence map›Paper›PMID 38196685›Full record

ArticleATS scholar2023

A Novel Provider Education Module to Enhance Detection of Alpha-1 Antitrypsin Deficiency.

Ross C Schumacher, Chia-Ying Chiu, Jovana Lubarda, Pakinam Aboulsaoud, Jennifer Bomberger, J Michael Wells

Open access · goldAbstract read
In one paragraph

Article in ATS scholar, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ross C SchumacherDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, and.ORCID https://orcid.org/0000-0002-7577-3599
Chia-Ying ChiuDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, and.
Jovana LubardaMedscape, LLC, New York, New York; and.
Pakinam AboulsaoudMedscape, LLC, New York, New York; and.
Jennifer BombergerMedscape, LLC, New York, New York; and.
J Michael WellsDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, and.ORCID https://orcid.org/0000-0001-9612-5454
Medscape · USUniversity of Alabama at Birmingham · US

Funding

Matrikines and COPD-PHR01HL148215 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WELLS, JAMES MICHAEL · 2019 to 2023
$2.4M
NHLBI NIH HHS R01 HL148215
6 · The paper itself

Abstract

Background: Alpha-1 antitrypsin deficiency (AATD) is the most common genetic risk factor for early-onset emphysema. However, AATD continues to be underrecognized and underdiagnosed. Provider awareness about AATD, concerns with testing costs, and limited understanding about therapeutic options contribute to its underdiagnosis. We hypothesized that provider education would improve awareness of AATD and improve screening. Objective: To evaluate the impact of a targeted provider education module on AATD screening. Methods: We developed a web-based education module to address barriers to screening for AATD, deployed the education module using the Medscape Education platform, assessed perceived healthcare provider confidence in AATD screening, and conducted a prospective pre and postintervention study of AATD testing practices at a high-volume academic outpatient subspecialty pulmonary clinic. Results: A total of 11,385 healthcare providers, including eight pulmonologists at our institution, completed the web-based education module. Confidence in identifying patients at high risk for AATD improved after completing the module ("not confident" in AATD screening was 7.7% postintervention compared with 19.4% preintervention). The rate of screening patients at high risk for AATD improved more than twofold (AATD screening rate 9.7% preintervention vs. 20.4% postintervention; Conclusion: Targeted healthcare provider education can improve the confidence in testing for AATD. Improvements in provider confidence corresponded to improvements in AATD screening in a subspecialty pulmonary clinic. More than one-fourth of screening tests suggested AATD, underpinning the value of testing in high-risk individuals.

Indexed as

alpha-1 antitrypsin deficiencychronic obstructive pulmonary diseaseeducation

Identifiers

PMID38196685
PMCPMC10773490
OpenAlexW4385950146

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.