Evidence map›Paper›PMID 38196553›Full record

ArticleProstate international2023

Dongho Shin, Byung Il Yoon, Soomin Kim, JunJie Piao, Kyung-Hwa Jeon, Youngjoo Kwon, Sang-Hyuck Park, Young Tae Koo, Jin-Soo Kim, Dong Sup Lee and 4 more

Open access · goldAbstract read
In one paragraph

Article in Prostate international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Nutrients · 2024
    Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Dongho ShinDepartment of Urology, College of Medicine, Catholic Kwandong University, Incheon, Korea.
Byung Il YoonDepartment of Urology, College of Medicine, Catholic Kwandong University, Incheon, Korea.
Soomin KimCatholic Integrative Medicine Research Institute, The Catholic University of Korea, Seoul, Korea.
JunJie PiaoCatholic Integrative Medicine Research Institute, The Catholic University of Korea, Seoul, Korea.
Kyung-Hwa JeonCollege of Pharmacy, Ewha Womans University, Seoul, Korea.
Youngjoo KwonCollege of Pharmacy, Ewha Womans University, Seoul, Korea.
Sang-Hyuck ParkInstitute of Cannabis Research, Colorado State University Pueblo, Pueblo, CO, USA.
Young Tae KooKwang Dong Pharmaceutical Co, Ltd., Seoul, Korea.
Jin-Soo KimKwang Dong Pharmaceutical Co, Ltd., Seoul, Korea.
Dong Sup LeeDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
U-Syn HaDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Sae Woong KimDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Hoon JangDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Woong Jin BaeDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Catholic University of Korea · KRBukwang Pharmaceutical (South Korea) · KRCatholic Kwandong University · KREwha Womans University · KRGreen Cross (South Korea) · KRColorado State University Pueblo · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: To evaluate the efficacy and safety of Materials and methods: From November 2020 to January 2022, participants with International Prostate Symptom Score (IPSS) of 12-19 in two centers were recruited and randomize into three groups: a CAG 500 mg/day group (CAG 500), a CAG 1000 mg/day group (CAG 1000), and a placebo group (PG). They were treated for 12 weeks. The primary endpoint was change of IPSS at the end of study from baseline. Secondary end points included change of prostate specific antigen (PSA), testosterone, dihydrotestosterone (DHT), maximum urinary flow rate (Q max), post-void residual volume (PVR), International Index of Erectile Function (IIEF), and drug safety. Results: A total of 103 patients were able to finish the study according to the study protocol. Total IPSS and sub-scores (residual urine sensation, frequency, weak stream, hesistancy, nocturia, and quality of life) in CAG 500 and CAG 1000 were significantly improved at the 12 Conclusions: CAG is well tolerated in patients with moderate LUTS. Treatment with CAG for 12 weeks has a therapeutic effect on moderate LUTS.

Indexed as

Cervi Parvum CornuDrug safetyIIEFIPSSPlant extracts

Identifiers

PMID38196553
PMCPMC10772165
OpenAlexW4386574249

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.