ArticleActa radiologica (Stockholm, Sweden : 1987)2024
A multicenter study of cervical cancer using quantitative diffusion-weighted imaging.
Article in Acta radiologica (Stockholm, Sweden : 1987), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Intravoxel incoherent motion imaging with improved image quality by deep learning reconstruction for prediction of lymph-vascular space invasion in patients with cervical cancer.Abdominal radiology (New York) · 2026Article
- Multi-institution longitudinal apparent diffusion coefficient measurements in a diffusion weighted imaging phantom at room temperature.Physics and imaging in radiation oncology · 2025Article
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7 authors.
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Abstract
backgroundParameters from diffusion-weighted imaging (DWI) have been increasingly used as imaging biomarkers for the diagnosis and monitoring of treatment responses in cancer. The consistency of DWI measurements across different centers remains uncertain, which limits the widespread use of quantitative DWI in clinical settings. PURPOSE: To investigate the consistency of quantitative metrics derived from DWI between different scanners in a multicenter clinical setting. MATERIAL AND
methodsA total of 193 patients with cervical cancer from four scanners (MRI1, MRI2, MRI3, and MRI4) at three centers were included in this retrospective study. DWI data were processed using the mono-exponential and intravoxel incoherent motion (IVIM) model, yielding the following parameters: apparent diffusion coefficient (ADC); true diffusion coefficient (D); pseudo-diffusion coefficient (D*); perfusion fraction (f); and the product of f and D* (fD*). Various parameters of cervical cancer obtained from different scanners were compared.
resultsThe parameters D and ADC derived from MRI1 and MRI2 were significantly different from those derived from MRI3 or MRI4 (
conclusionScanners of the same model by the same vendor can yield close measurements of the ADC and IVIM parameters. The perfusion parameters showed higher consistency among the different scanners.
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