Evidence map›Paper›PMID 38195977›Full record

ArticleScientific reports2024

Approaching expert-level accuracy for differentiating ACL tear types on MRI with deep learning.

Yang Xue, Shu Yang, Wenjie Sun, Hui Tan, Kaibin Lin, Li Peng, Zheng Wang, Jianglin Zhang

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Recent Advances in Musculoskeletal Radiology: Bridging Innovation and Clinical Application.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. AI for Lesion Detection in Musculoskeletal Radiology.Journal of the Korean Society of Radiology · 2025
    Review
  9. Article
  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yang Xue *School of Computer Science, Hunan First Normal University, Changsha, 410205, China.
Shu Yang *Department of Orthopaedic, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, 410002, China.
Wenjie SunDepartment of Radiology, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, 410002, China.
Hui TanDepartment of Radiology, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, 410002, China.
Kaibin LinSchool of Computer Science, Hunan First Normal University, Changsha, 410205, China.
Li PengSchool of Computer Science, Hunan First Normal University, Changsha, 410205, China.
Zheng WangSchool of Computer Science, Hunan First Normal University, Changsha, 410205, China. w8614@hotmail.com.
Jianglin ZhangDepartment of Dermatology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, 518020, Guangdong, China. zhang.jianglin@szhospital.com.

Funding

Hunan provincial nature science foundation of China 2022JJ30189Hunan provincial nature science foundation of China 2022JJ40229National Natural Science Foundation of China 82073018Scientific Research Fund of Hunan Provincial Education Department 23A0643Shenzhen Science and Technology Innovation Committee JCYJ20210324113001005Shenzhen Science and Technology Innovation Committee JCYJ20210324114212035Teaching Reform Research Project of Universities in Hunan Province HNJG-2021-1120
6 · The paper itself

Abstract

Treatment for anterior cruciate ligament (ACL) tears depends on the condition of the ligament. We aimed to identify different tear statuses from preoperative MRI using deep learning-based radiomics with sex and age. We reviewed 862 patients with preoperative MRI scans reflecting ACL status from Hunan Provincial People's Hospital. Based on sagittal proton density-weighted images, a fully automated approach was developed that consisted of a deep learning model for segmenting ACL tissue (ACL-DNet) and a deep learning-based recognizer for ligament status classification (ACL-SNet). The efficacy of the proposed approach was evaluated by using the sensitivity, specificity and area under the receiver operating characteristic curve (AUC) and compared with that of a group of three orthopedists in the holdout test set. The ACL-DNet model yielded a Dice coefficient of 98% ± 6% on the MRI datasets. Our proposed classification model yielded a sensitivity of 97% and a specificity of 97%. In comparison, the sensitivity of alternative models ranged from 84 to 90%, while the specificity was between 86 and 92%. The AUC of the ACL-SNet model was 99%, demonstrating high overall diagnostic accuracy. The diagnostic performance of the clinical experts as reflected in the AUC was 96%, 92% and 88%, respectively. The fully automated model shows potential as a highly reliable and reproducible tool that allows orthopedists to noninvasively identify the ACL status and may aid in optimizing different techniques, such as ACL remnant preservation, for ACL reconstruction.

Indexed as

Anterior Cruciate Ligament InjuriesDeep LearningAnterior Cruciate Ligament ReconstructionBrain NeoplasmsGliomaHumansMagnetic Resonance Imaging

Identifiers

PMID38195977
PMCPMC10776725

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.