Evidence map›Paper›PMID 38195756›Full record

ArticleNPJ Parkinson's disease2024

Neurocognitive correlates of semantic memory navigation in Parkinson's disease.

Felipe Diego Toro-Hernández, Joaquín Migeot, Nicolás Marchant, Daniela Olivares, Franco Ferrante, Raúl González-Gómez, Cecilia González Campo, Sol Fittipaldi, Gonzalo M Rojas-Costa, Sebastian Moguilner and 5 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in NPJ Parkinson's disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Cognitive Phenotyping of Parkinson's Disease Patients Via Digital Analysis of Spoken Word Properties.Movement disorders : official journal of the Movement Disorder Society · 2025
    Article
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  7. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 6 countries.

Felipe Diego Toro-Hernández *Graduate Program in Neuroscience and Cognition, Federal University of ABC, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-1237-343X
Joaquín Migeot *Center for Social and Cognitive Neuroscience, School of Psychology, Universidad Adolfo Ibáñez, Santiago, Chile.
Nicolás MarchantCenter for Social and Cognitive Neuroscience, School of Psychology, Universidad Adolfo Ibáñez, Santiago, Chile.
Daniela OlivaresCenter for Social and Cognitive Neuroscience, School of Psychology, Universidad Adolfo Ibáñez, Santiago, Chile.
Franco FerranteCognitive Neuroscience Center, Universidad de San Andrés, Buenos Aires, Argentina.ORCID http://orcid.org/0000-0002-9455-2214
Raúl González-GómezCenter for Social and Cognitive Neuroscience, School of Psychology, Universidad Adolfo Ibáñez, Santiago, Chile.ORCID http://orcid.org/0000-0003-2341-011X
Cecilia González CampoCognitive Neuroscience Center, Universidad de San Andrés, Buenos Aires, Argentina.
Sol FittipaldiLatin American Brain Health Institute, Universidad Adolfo Ibáñez, Santiago, Chile.ORCID http://orcid.org/0000-0001-7704-3349
Gonzalo M Rojas-CostaDepartment of Radiology, Clínica las Condes, Santiago, Chile.ORCID http://orcid.org/0000-0002-6228-2678
Sebastian MoguilnerGlobal Brain Health Institute, University of California, San Francisco, California, USA; & Trinity College, Dublin, Ireland.
Andrea SlachevskyMemory and Neuropsychiatric Center (CMYN), Neurology Department, Hospital del Salvador & Faculty of Medicine, University of Chile, Santiago, Chile.
Pedro Chaná CuevasFacultad de Ciencias Médicas, Universidad de Santiago de Chile, Santiago, Chile.
Agustín IbáñezLatin American Brain Health Institute, Universidad Adolfo Ibáñez, Santiago, Chile.ORCID http://orcid.org/0000-0001-6758-5101
Sergio ChaigneauCenter for Social and Cognitive Neuroscience, School of Psychology, Universidad Adolfo Ibáñez, Santiago, Chile.ORCID http://orcid.org/0000-0001-8642-6325
Adolfo M GarcíaLatin American Brain Health Institute, Universidad Adolfo Ibáñez, Santiago, Chile. adolfo.garcia@gbhi.org.ORCID http://orcid.org/0000-0002-6936-0114
Adolfo Ibáñez University · CLConsejo Nacional de Investigaciones Científicas y Técnicas · ARUniversidad de Santiago de Chile · CLClínica Las Condes · CLUniversidad del Desarrollo · CLUniversity of California, San Francisco · US

Funding

TDP-43 Loss-of-Function: Biology to BiomarkersP01AG019724 · NIA · UNIVERSITY OF PENNSYLVANIA · PI Jennifer Merrilees · 2002 to 2026
$67.2M
An automated machine learning approach to language changes in Alzheimer’s disease and frontotemporal dementia across Latino and English-speaking populationsR01AG075775 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MARIA LUISA GORNO TEMPINI, Adolfo Martin Garcia · 2023 to 2026
$7.2M
US-South American Initiative for Genetic-Neural-Behavioral Interactions in Human Neurodegenerative ResearchR01AG057234 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Claudia Duran-Aniotz, Agustin M. Ibanez · 2019 to 2026
$6.1M
Circadian Disturbance and Dementia in Latin AmericaR01AG083799 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI Kun Hu, Agustin M. Ibanez · 2023 to 2026
$3.0M
NIA NIH HHS P01 AG019724NIA NIH HHS R01 AG057234NIA NIH HHS R01 AG075775NIA NIH HHS R01 AG083799
6 · The paper itself

Abstract

Cognitive studies on Parkinson's disease (PD) reveal abnormal semantic processing. Most research, however, fails to indicate which conceptual properties are most affected and capture patients' neurocognitive profiles. Here, we asked persons with PD, healthy controls, and individuals with behavioral variant frontotemporal dementia (bvFTD, as a disease control group) to read concepts (e.g., 'sun') and list their features (e.g., hot). Responses were analyzed in terms of ten word properties (including concreteness, imageability, and semantic variability), used for group-level comparisons, subject-level classification, and brain-behavior correlations. PD (but not bvFTD) patients produced more concrete and imageable words than controls, both patterns being associated with overall cognitive status. PD and bvFTD patients showed reduced semantic variability, an anomaly which predicted semantic inhibition outcomes. Word-property patterns robustly classified PD (but not bvFTD) patients and correlated with disease-specific hypoconnectivity along the sensorimotor and salience networks. Fine-grained semantic assessments, then, can reveal distinct neurocognitive signatures of PD.

Identifiers

PMID38195756
PMCPMC10776628
OpenAlexW4390724295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.