Evidence map›Paper›PMID 38195691›Full record

ArticleScientific reports2024

Association of PFDeA exposure with hypertension (NHANES, 2013-2018).

Jie Li, Suling Ye, Zeyuan Zhao, Zhao Xue, Shupeng Ren, Yue Guan, Chuang Sun, Qiying Yao, Liang Chen

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.5field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. The role of per- and polyfluoroalkyl substances in cognitive impairment and dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jie LiDepartment of Cardiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.
Suling YeDepartment of Cardiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.
Zeyuan ZhaoDepartment of Cardiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.
Zhao XueDepartment of Cardiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.
Shupeng RenDepartment of Cardiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.
Yue GuanDepartment of Cardiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.
Chuang SunDepartment of Cardiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.
Qiying YaoDepartment of Physiology, Dalian Medical University, Dalian, China. 81317121@qq.com.
Liang ChenDepartment of Cardiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, China. dyeyarrhythmia@163.com.
Dalian Medical University · CNSecond Affiliated Hospital of Dalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Perfluoroalkyl and polyfluoroalkyl substances (PFASs) is a series of artificial compounds which is associated with human health. However, there are few studies on the relationship between PFASs and hypertension. In this study, we examined the association between different kinds of PFASs and hypertension. Multivariable logistic regression and subgroup analysis were adopted to assess the associations between PFASs and hypertension. Spline smoothing plots and linear regression were used to assess the relationship between PFASs and blood pressure. We found a positive association between serum PFDeA concentrations and the prevalence of hypertension after fully adjusting confounders (OR = 1.2, P = 0.01), but other types of PFASs showed no positive results. Subgroup analysis stratified by ethnicity showed there was a stronger relationship among non-Hispanics than Hispanics. Serum PFDeA concentrations were positively associated with systolic pressure (β = 0.7, P< 0.01) and diastolic blood pressure (β = 0.8, P< 0.01) among non-Hispanics who did not take antihypertensive drugs. This study showed that PFDeA exposure was associated with hypertension in Americans who identify as non-Hispanic. There was a positive association between PFDeA and blood pressure in non-Hispanic Americans who did not take antihypertensive drugs.

Indexed as

FluorocarbonsHypertensionAntihypertensive AgentsBlood PressureHumansNutrition SurveysAntihypertensive AgentsFluorocarbons

Identifiers

PMID38195691
PMCPMC10776849
OpenAlexW4390725881

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.