ArticleBMC nutrition2024
Low plasma vitamin D is associated with increased 28-day mortality and worse clinical outcomes in critically ill patients.
Article in BMC nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.
- Vitamin D supplementation and mortality among critically ill adults: a systematic review and meta-analysis.Frontiers in nutrition · 2026Pooled it
- Article
- Association between vitamin D supplementation and mortality in elderly critically ill patients: a retrospective propensity score-matched cohort study.Frontiers in nutrition · 2026Article
- The efficacy of high-protein nutritional support on mortality, clinical outcomes, and nutritional adequacy in critically ill patients: a double‑center randomized controlled trial.Nutrition & metabolism · 2025Article
- Knowledge, attitudes, and practices (KAP) regarding nutrition among bodybuilders of Zanjan, Northwest of Iran: a cross-sectional study.BMC sports science, medicine & rehabilitation · 2025Article
- Protein intake and clinical outcomes in critically ill patients: A dose-response and pairwise meta-analysis of randomized controlled trials.Health promotion perspectives · 2025Review
- Low plasma vitamin D is associated with increased 28-day mortality and worse clinical outcomes in critically ill patients.BMC nutrition · 2024Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND &
objectivePatients in the intensive care unit have a high prevalence of vitamin D deficiency (VDD). In the present study, clinical outcomes in the ICU were analyzed with vitamin D status. MATERIALS AND
methodsIn this prospective, multicenter study, sampling was conducted on seven ICUs in three hospitals. Within the first 24 h of ICU admission, patient's serum vitamin D levels were measured, and their disease severity was monitored using the scores of acute physiologic assessment and chronic health evaluation II (APACHE II), sequential organ failure assessment (SOFA), and the modified Nutrition Risk in Critically ill (mNUTRIC) score.
resultsA total of 236 patients were enrolled in this study, of which 163 (69.1%) had lower vitamin D levels than 20 ng/ml upon ICU admission. The patients with VDD had higher APACHE II scores)P = 0.02), SOFA scores (P < 0.001), and mNUTRIC scores (P = 0.01). Patients with sufficient levels of vitamin D (> 30 ng/ml) had a shorter stay at ICU (P < 0.001). VDD was independently associated with 28-day mortality (OR: 4.83; 95% CI: 1.63-14.27; P = 0.004).
conclusionThe data showed that VDD was common among the critically ill and was related to a more severe course of illness and a higher mortality rate.
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