Evidence map›Paper›PMID 38195493›Full record

ReviewJournal of health, population, and nutrition2024

Hand grip strength as a proposed new vital sign of health: a narrative review of evidences.

Raju Vaishya, Anoop Misra, Abhishek Vaish, Nicola Ursino, Riccardo D'Ambrosi

2 registry-linked trialsAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of health, population, and nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 215 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
215citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07597850 phase2recruitingnot on this mapstarted 2026, after this paper: background citation

Effects of Traditional Chinese Medicine (TCM) Formula vs. HMB on Muscle Strength and Bone Status in Pre-Frail Elders: A Comparative Study

TypeinterventionalSponsorTri-Service General Hospital (TSGH)Ran2026 to 2026Enrolled90ConditionsPre-Frailty, Sarcopenia, Muscle Atrophy or Weakness, OsteoporosisArmsTCM Formula, HMB (beta-Hydroxy-beta-methylbutyrate)
NCT07675148 narecruitingnot on this mapstarted 2025, after this paper: background citation

Cooking Classes as a Family-based Intervention for Weight Reduction: Effects on Dietary Quality and Weight Management in Abu Dhabi (United Arab Emirates)

TypeinterventionalSponsorInstitute for Healthier Living Abu DhabiRan2025 to 2026Enrolled250ConditionsObesity & Overweight, Culinary MedicineArmsCulinary Medicine Healthy Cooking and Home Meal Implementation Program
3 · Its place in the literature

Who cites it

215 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. A Combination ofInternational journal of medical sciences · 2025
    Trial
  13. Trial
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Low handgrip strength in advanced cancer: associated factors and clinical implications in palliative care.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article

155 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Raju VaishyaDepartment of Orthopaedics, Indraprastha Apollo Hospitals, Sarita Vihar, New Delhi, 10076, India.
Anoop MisraDepartment of Endocrinology, C-DOC Fortis Hospital, Nehru Place, New Delhi, India.
Abhishek VaishDepartment of Orthopaedics, Indraprastha Apollo Hospitals, Sarita Vihar, New Delhi, 10076, India.
Nicola UrsinoIRCCS Ospedale Galeazzi - Sant'Ambrogio, Milan, Italy.
Riccardo D'AmbrosiIRCCS Ospedale Galeazzi - Sant'Ambrogio, Milan, Italy. riccardo.dambrosi@hotmail.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hand grip strength (HGS) serves as a fundamental metric in assessing muscle function and overall physical capability and is particularly relevant to the ageing population. HGS holds an important connection to the concept of sarcopenia, which encompasses the age-related decline in muscle mass, strength, and function. It has also been reported to indicate the health of an individual. We reviewed the interplay between HGS and various health parameters, including morbidity and mortality, by carrying out a literature search on PubMed, Scopus and Google Scholar between 10 and 30 August 2023, to identify the relevant papers on the relationship between health and HGS. We used several keywords like 'hand grip strength', 'muscle strength, 'sarcopenia', 'osteosarcopenia', 'health biomarker', 'osteoporosis', and 'frailty', to derive the appropriate literature for this review. This review has shown that the HGS can be measured reliably with a hand-held dynamometer. The cut-off values are different in various populations. It is lower in Asians, women, less educated and privileged, and those involved in sedentary work. Several diseases have shown a correlation with low HGS, e.g., Type 2 diabetes, cardiovascular disease, stroke, chronic kidney and liver disease, some cancers, sarcopenia and fragility fractures. The low HSG is also associated with increased hospitalization, nutritional status, overall mortality and quality of life. We believe that there is adequate evidence to show that HGS stands as an important biomarker of health. Its utility extends to the identification of diverse health issues and its potential as a new vital sign throughout the lifespan.

Indexed as

Diabetes Mellitus, Type 2SarcopeniaBiomarkersFemaleHand StrengthHumansQuality of LifeVital SignsBiomarkersBiomarkerDiabetesFrailtyHandgrip strengthHealthMuscleOsteoporosisSarcopeniaVital sign

Identifiers

PMID38195493
PMCPMC10777545

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.