Evidence map›Paper›PMID 38195456›Full record

ArticleJournal of nanobiotechnology2024

Synergistic cerium oxide nanozymes: targeting DNA damage and alleviating tumor hypoxia for improved NSCLC radiotherapy efficiency.

Jie Liu, Chengxiang Liu, Jinghua Tang, Qiao Chen, Yan Yu, Yan Dong, Jie Hao, Wei Wu

Open access · goldAbstract read
In one paragraph

Article in Journal of nanobiotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Targeting glutathione metabolism for tumor radiosensitization (Review).International journal of molecular medicine · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jie Liu *Department of Cardiothoracic Surgery, Southwest Hospital, Army Medical University, 30 Gaotanyan Main St, Chongqing, 400038, China.
Chengxiang Liu *Department of Oncology, Southwest Hospital, Army Medical University, 30 Gaotanyan Main St, Chongqing, 400038, China.
Jinghua Tang *Department of Cardiothoracic Surgery, Southwest Hospital, Army Medical University, 30 Gaotanyan Main St, Chongqing, 400038, China.
Qiao ChenDepartment of Cardiothoracic Surgery, Southwest Hospital, Army Medical University, 30 Gaotanyan Main St, Chongqing, 400038, China.
Yan YuDepartment of Cardiothoracic Surgery, Southwest Hospital, Army Medical University, 30 Gaotanyan Main St, Chongqing, 400038, China.
Yan DongDepartment of Oncology, Southwest Hospital, Army Medical University, 30 Gaotanyan Main St, Chongqing, 400038, China. yandong@tmmu.edu.cn.
Jie HaoDepartment of Oncology, Southwest Hospital, Army Medical University, 30 Gaotanyan Main St, Chongqing, 400038, China. haojie724@sina.com.
Wei WuDepartment of Cardiothoracic Surgery, Southwest Hospital, Army Medical University, 30 Gaotanyan Main St, Chongqing, 400038, China. wuweiyahoo@sohu.com.
Southwest Hospital · CNArmy Medical University · CN

Funding

National Natural Science Foundation of China 81803028the Doctoral Research Innovation Project CYB21228the Science and Technology Research Program Project of Chongqing Education Commission KJQN202212802
6 · The paper itself

Abstract

Radiotherapy (RT) is one of the important treatment modalities for non-small cell lung cancer (NSCLC). However, the maximum radiation dose that NSCLC patient can receive varies little. Therefore, the exploitation of novel RT sensitization approaches is a critical need for the clinical treatment. RT resistance in NSCLC is linked to tumor microenvironment (TME) hypoxia, cell cycle arrest and associated genetic alterations. Here, we designed a novel method for targeted delivery of quercetin (QT) and CeO

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsCeriumDNA DamageHumansHydrogen PeroxideHypoxiaQuercetinTumor HypoxiaTumor Microenvironmentceric oxideCeriumHydrogen PeroxideQuercetinCeO2NSCLCQuercetinRadiotherapyZIF-8

Identifiers

PMID38195456
PMCPMC10777519
OpenAlexW4390748765

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.