Evidence map›Paper›PMID 38195453›Full record

ArticleBMC gastroenterology2024

Growth development of children and adolescents with inflammatory bowel disease in the period 2000-2014 based on data of the Saxon pediatric IBD registry: a population-based study.

Xueming Zhou, Ivana Kern, Ulrike Rothe, Olaf Schoffer, Jens Weidner, Thomas Richter, Martin W Laass, Joachim Kugler, Ulf Manuwald

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In one paragraph

Article in BMC gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xueming Zhou *Health Sciences/Public Health, Institute and Policlinic for Occupational and Social Medicine, Faculty of Medicine "Carl Gustav Carus", TU Dresden, 01309, Dresden, Germany. Xueming.zhou@mailbox.tu-dresden.de.
Ivana Kern *Health Sciences/Public Health, Institute and Policlinic for Occupational and Social Medicine, Faculty of Medicine "Carl Gustav Carus", TU Dresden, 01309, Dresden, Germany.
Ulrike RotheGWT of the TU Dresden, Dresden, Germany.
Olaf SchofferCenter for Evidence-Based Healthcare, University Hospital and Faculty of Medicine, Dresden, Germany.
Jens WeidnerCenter for Medical Informatics, Institute for Medical Informatics and Biometry, Faculty of Medicine "Carl Gustav Carus", TU Dresden, Dresden, Germany.
Thomas RichterClinic for Children and Adolescents, Hospital St. Georg, Leipzig, Germany.
Martin W LaassFaculty of Medicine "Carl Gustav Carus", University Hospital for Children and Adolescents, TU Dresden, Dresden, Germany.
Joachim KuglerHealth Sciences/Public Health, Institute and Policlinic for Occupational and Social Medicine, Faculty of Medicine "Carl Gustav Carus", TU Dresden, 01309, Dresden, Germany.
Ulf ManuwaldUniversity of Applied Sciences Dresden (FHD), Dresden, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence of inflammatory bowel disease (IBD) in children is on the increase worldwide. Growth disorders are common in pediatric patients with inflammatory bowel disease. The aim of this paper is to investigate anthropometric indicators, including height and weight in children with inflammatory bowel disease in Saxony, one of the German federal states, and to evaluate growth trends in patients by comparing their height and weight with that of healthy children in Germany.

methodsIn Saxony, all children and adolescents with IBD were registered in the Saxon Pediatric IBD Registry from 2000 to 2014. The data used are therefore based on a total area-wide survey over 15 years. For this study, 421 datasets of children and adolescents aged 0-14 years with Crohn's disease (CD) (n = 291) or ulcerative colitis (UC) (n = 130) were analyzed. Z-score and percentile calculations were used to compare differences between IBD patients and the general population.

resultsThe children with CD or UC (both sexes) had a significant lower weight at diagnosis (the mean weight z-score had negative values) versus the general population. The weight values lay mostly below P50 (the 50th percentile, median), more precisely, mostly between P10 and P50 of the body weight child growth curve for corresponding sexes (KiGGS 2003-2006). The height values of both sexes at diagnosis lay also mostly below P50 (the 50th percentile, median) of the child body growth curve for corresponding sexes (KiGGS 2003-2006), i.e. the mean height z-score was negative. But only the children with CD had a significant lower height, more precisely, mostly between P25 and P50 versus the general population (KIGGS). For children with UC the difference was not significant.

conclusionIn pediatric patients with IBD the possibility of growth disturbance, mainly in the form of weight retardation, is very probable.

Indexed as

Colitis, UlcerativeCrohn DiseaseInflammatory Bowel DiseasesAdolescentChildFemaleHumansMaleRegistriesResearchChildCrohn’s diseaseGrowth disordersGrowth failureHeightInflammatory bowel diseaseRetardationUlcerative colitisWeight

Identifiers

PMID38195453
PMCPMC10775659

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.