ArticleBMC infectious diseases2024
Association between lactate-to-albumin ratio and 28-days all-cause mortality in patients with sepsis-associated liver injury: a retrospective cohort study.
Article in BMC infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Association Between Lactate Trajectories and Clinical Outcomes in Critically Ill Patients with Sepsis-Associated Liver Injury.Journal of clinical medicine · 2026Article
- Dynamic Lactate-to-Albumin Ratio Trajectories and Outcomes in Sepsis-Associated Acute Kidney Injury: Evidence From MIMIC-IV and a Multicenter Chinese Cohort.JMIR medical informatics · 2026Observational
- Biomimetic Targeted Drug Delivery for Liver Failure in Abdominal Sepsis: Focus on Autologous Erythrocyte Ghosts.International journal of molecular sciences · 2026Review
- Lactate-to-albumin ratio as a short‑term prognostic biomarker in atrial fibrillation.Journal of cardiothoracic surgery · 2026Article
- Association between lactate-to-albumin ratio and mortality in patients with sepsis-induced coagulopathy: a retrospective cohort study.Scientific reports · 2026Article
- Clinical utility of the lactate-to-albumin ratio for predicting mortality in elderly severe acute pancreatitis.Frontiers in medicine · 2026Article
- Association Between the Lactate-to-Albumin Ratio and ICU/In-Hospital Mortality in Critically Ill Patients With Comorbid Type 2 Diabetes Mellitus : A Cohort Study Utilizing the MIMIC-IV Database.Emergency medicine international · 2026Article
- Early prognostic value of the lactate-to-albumin ratio in severe acute pancreatitis with acute respiratory distress syndrome.Frontiers in medicine · 2026Article
- Early enteral nutrition and dynamic metabolic-inflammatory trajectories in sepsis: a retrospective cohort study.Frontiers in medicine · 2026Article
- Association between serum phosphate levels and 28-day mortality in patients with sepsis-associated liver injury: a cohort study.BMC infectious diseases · 2025Article
- Association of the Lactate/Albumin Ratio with Mortality and Hypovolemia in Critically Ill Patients: A Retrospective Cohort Study.Journal of clinical medicine · 2025Article
- Prognostic value of albumin-corrected anion gap in critically ill patients with sepsis-associated liver injury: a retrospective study.BMC infectious diseases · 2025Article
- Association between lactate-to-albumin ratio and mortality in hepatic failure: a retrospective cohort study.BMC infectious diseases · 2025Article
- Association between lactate-albumin ratio and 28-day mortality in patients with sepsis-associated acute kidney injury: a retrospective cohort study.Scientific reports · 2025Article
- Association between lactate-to-albumin ratio and all-cause mortality in critically ill cirrhotic patients with sepsis: a retrospective analysis of the MIMIC-IV database.BMC gastroenterology · 2025Article
- Aspirin is associated with improved 30-day mortality in patients with sepsis-associated liver injury: a retrospective cohort study based on MIMIC IV database.Frontiers in pharmacology · 2025Article
- Lactate to albumin ratio as a prognostic marker for all-cause mortality in patients with venous thromboembolism: a retrospective cohort study.Frontiers in cardiovascular medicine · 2025Article
- The association of serum albumin with 28 day mortality in critically ill patients undergoing dialysis: a secondary analysis based on the eICU collaborative research database.European journal of medical research · 2024Article
- Kinetics of the Lactate to Albumin Ratio in New Onset Sepsis: Prognostic Implications.Diagnostics (Basel, Switzerland) · 2024Article
- Association between red cell distribution width and 30-day mortality in patients with sepsis-associated liver injury: a retrospective cohort study.Frontiers in medicine · 2024Article
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Authors and funding
7 authors.
Funding
Abstract
backgroundThe mortality rate of sepsis-associated liver injury (SALI) is relatively high, but there is currently no authoritative prognostic criterion for the outcome of SALI. Meanwhile, lactate-to-albumin ratio (LAR) has been confirmed to be associated with mortality rates in conditions such as sepsis, heart failure, and respiratory failure. However, there is a scarcity of research reporting on the association between LAR and SALI. This study aimed to elucidate the association between LAR and the 28-day mortality rate of SALI.
methodsIn this retrospective cohort study, data were obtained from the Medical Information Mart for Intensive Care IV (v2.2). Adult patients with SALI were admitted to the intensive care unit in this study. The LAR level at admission was included, and the primary aim was to assess the relationship between the LAR and 28-day all-cause mortality.
resultsA total of 341 patients with SALI (SALI) were screened. They were divided into a survival group (241) and a non-survival group (100), and the 28-day mortality rate was 29.3%. Multivariable Cox regression analysis revealed that for every 1-unit increase in LAR, the 28-day mortality risk for SALI patients increased by 21%, with an HR of 1.21 (95% CI 1.11 ~ 1.31, p < 0.001).
conclusionsThis study indicates that in patients with SALI, a higher LAR is associated with an increased risk of all-cause mortality within 28 days of admission. This suggests that LAR may serve as an independent risk factor for adverse outcomes in SALI patients.
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