Evidence map›Paper›PMID 38195167›Full record

ArticleBMJ open2024

The Tuberculosis Sentinel Research Network (TB-SRN) of the International epidemiology Databases to Evaluate AIDS (IeDEA): protocol for a prospective cohort study in Africa, Southeast Asia and Latin America.

Leslie A Enane, Stephany N Duda, Thida Chanyachukul, Carolyn Bolton-Moore, Neelima Navuluri, Eugène Messou, Nana Mbonze, LaQuita R McDade, Marina Cruvinel Figueiredo, Jeremy Ross and 20 more

Abstract read
In one paragraph

Article in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Leslie A EnaneThe Ryan White Center for Pediatric Infectious Diseases and Global Health, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA lenane@iu.edu.ORCID 0000-0001-8390-5881
Stephany N DudaDepartment of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Thida ChanyachukulTREAT Asia/amfAR - The Foundation for AIDS Research, Bangkok, Thailand.
Carolyn Bolton-MooreCenter for Infectious Disease Research in Zambia (CIDRZ), Lusaka, Zambia.
Neelima NavuluriDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0002-1499-8073
Eugène MessouCentre de Prise en Charge de Recherche et de Formation (Aconda-CePReF), Abidjan, Côte d'Ivoire.
Nana MbonzeKinshasa School of Public Health, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
LaQuita R McDadeVanderbilt Institute of Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Marina Cruvinel FigueiredoVanderbilt Tuberculosis Center, Division of Infectious Diseases, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Jeremy RossTREAT Asia/amfAR - The Foundation for AIDS Research, Bangkok, Thailand.
Denise EvansHealth Economics and Epidemiology Research Office, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Lameck DieroDepartment of Medicine, Moi University College of Health Sciences, Eldoret, Kenya.
Robert AkpataUniversité de Bordeaux, Bordeaux, France.
Natalia ZotovaDivision of General Internal Medicine, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA.
Aimee FreemanJohns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Marie Flore PierreThe Haitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), Port-au-Prince, Haiti.
Dhanushi RupasingheThe Kirby Institute, UNSW, Sydney, New South Wales, Australia.
Marie BallifInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Helen ByakwagaMbarara University of Science and Technology Faculty of Medicine, Mbarara, Uganda.
Nathalie de CastroUniversité de Bordeaux, Bordeaux, France.
Martine TabalaKinshasa School of Public Health, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Timothy R SterlingVanderbilt Tuberculosis Center, Division of Infectious Diseases, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Annette H SohnTREAT Asia/amfAR - The Foundation for AIDS Research, Bangkok, Thailand.
Lukas FennerInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Kara Wools-KaloustianIndiana University Center for Global Health Equity, Indianapolis, Indiana, USA.
Armel PodaCentre Hospitalier Universitaire Sourô Sanou, Bobo Dioulasso, Burkina Faso.
Marcel YotebiengDivision of General Internal Medicine, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA.
Robin HuebnerDivision of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Olivier MarcyUniversité de Bordeaux, Bordeaux, France.ORCID 0000-0003-3350-112X
International epidemiology Databases to Evaluate AIDS

Funding

North American AIDS Cohorts on Collaboration and Design (NAACCORD)U01AI069918 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Keri Nicole Althoff, RICHARD Douglas MOORE · 2006 to 2026
$65.2M
East Africa International Epidemiology Database to evaluate AIDS (IeDEA) Regional ConsortiumU01AI069911 · NIAID · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI Leslie Anne Enane, AGGREY SEMWENDERO SEMEERE · 2006 to 2026
$57.7M
Observational Antiretroviral Studies In Southern Africa (OASIS) CollaborationU01AI069924 · NIAID · UNIVERSITAT BERN · PI Cleophas Chimbetete, Mary-Ann Davies · 2006 to 2026
$55.9M
The Asia-Pacific HIV Research CollaborationU01AI069907 · NIAID · FOUNDATION FOR AIDS RESEARCH · PI ANNETTE H SOHN · 2006 to 2026
$44.8M
CCASAnet: Caribbean, Central and South America NetworkU01AI069923 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Pedro Enrique Cahn, Jessica L Castilho · 2006 to 2026
$41.6M
"Enhancing Cancer Research in Central Africa IeDEA"U01AI096299 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Denis Nash, Marcel Yotebieng · 2011 to 2026
$35.8M
WADA (West Africa Database on Antiretroviral Therapy) CollaborationU01AI069919 · NIAID · UNIVERSITY OF BORDEAUX II · PI Didier Koumavi Ekouevi, Antoine Jaquet · 2006 to 2026
$29.9M
Harmonist: A Scalable Toolkit for Standardizing and Coordinating Data Sharing Across International Research NetworksR24AI124872 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Stephany Norah Duda · 2016 to 2026
$12.5M
Neuro HPA Project 1U54AG062334 · NIA · EMORY UNIVERSITY · PI Ighovwerha Ofotokun · 2018 to 2026
$12.2M
Regional Prospective Observational Research in Tuberculosis (RePORT) – Brazil NetworkU01AI172064 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BRUNO DE BEZERRIL ANDRADE, TIMOTHY R STERLING · 2023 to 2026
$4.0M
Developing an Instrument to Assess Adolescent Risk for Disengagement from HIV CareK23HD095778 · NICHD · INDIANA UNIVERSITY INDIANAPOLIS · PI ENANE, LESLIE ANNE · 2018 to 2022
$786k
NIAID NIH HHS R24 AI124872NIAID NIH HHS U01 AI069907NIAID NIH HHS U01 AI069911NIAID NIH HHS U01 AI069918NIAID NIH HHS U01 AI069919NIAID NIH HHS U01 AI069923NIAID NIH HHS U01 AI069924NIAID NIH HHS U01 AI096299NIAID NIH HHS U01 AI172064NIA NIH HHS U54 AG062334NICHD NIH HHS K23 HD095778NICHD NIH HHS L40 HD103261
6 · The paper itself

Abstract

introductionTuberculosis (TB) is a leading infectious cause of death globally. It is the most common opportunistic infection in people living with HIV, and the most common cause of their morbidity and mortality. Following TB treatment, surviving individuals may be at risk for post-TB lung disease. The TB Sentinel Research Network (TB-SRN) provides a platform for coordinated observational TB research within the International epidemiology Databases to Evaluate AIDS (IeDEA) consortium. METHODS AND ANALYSIS: This prospective, observational cohort study will assess treatment and post-treatment outcomes of pulmonary TB (microbiologically confirmed or clinically diagnosed) among 2600 people aged ≥15 years, with and without HIV coinfection, consecutively enrolled at 16 sites in 11 countries, across 6 of IeDEA's global regions. Data regarding clinical and sociodemographic factors, mental health, health-related quality of life, pulmonary function, and laboratory and radiographic findings will be collected using standardised questionnaires and data collection tools, beginning from the initiation of TB treatment and through 12 months after the end of treatment. Data will be aggregated for proposed analyses. ETHICS AND DISSEMINATION: Ethics approval was obtained at all implementing study sites, including the Vanderbilt University Medical Center Human Research Protections Programme. Participants will provide informed consent; for minors, this includes both adolescent assent and the consent of their parent or primary caregiver. Protections for vulnerable groups are included, in alignment with local standards and considerations at sites. Procedures for requesting use and analysis of TB-SRN data are publicly available. Findings from TB-SRN analyses will be shared with national TB programmes to inform TB programming and policy, and disseminated at regional and global conferences and other venues.

Indexed as

Acquired Immunodeficiency SyndromeTuberculosisAdolescentAfricaAsia, SoutheasternHumansLatin AmericaObservational Studies as TopicProspective StudiesQuality of LifeHIV & AIDSObservational StudyTuberculosis

Identifiers

PMID38195167
PMCPMC10806577

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.