Evidence map›Paper›PMID 38195138›Full record

ArticleNeurosciences (Riyadh, Saudi Arabia)2024

Pioglitazone and barriers to effective post-stroke comorbidity management in stroke survivors with diabetes.

Hala Azhari, Jonathan Hewitt, Alexander Smith, Martin O'Neill, Terence Quinn, Jesse Dawson

Open access · greenAbstract read
In one paragraph

Article in Neurosciences (Riyadh, Saudi Arabia), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hala AzhariFrom the College of Medicine and Pharmacy (Azhari), Umm Al-Qura University, Makkah, Kingdom of Saudi Arabia, from the School of Cardiovascular and Metabolic Health (Azhari, Quinn, Dawson), University of Glasgow, Glasgow, from the School of Geriatric Medicine Centre (Hewitt, O'Neill), Cardiff University, and from the Clinical Research and Innovation Centre (Smith), Aneurin Bevan University Health Board, Newport, United Kingdom.ORCID https://orcid.org/0000-0002-3010-3057
Jonathan HewittFrom the College of Medicine and Pharmacy (Azhari), Umm Al-Qura University, Makkah, Kingdom of Saudi Arabia, from the School of Cardiovascular and Metabolic Health (Azhari, Quinn, Dawson), University of Glasgow, Glasgow, from the School of Geriatric Medicine Centre (Hewitt, O'Neill), Cardiff University, and from the Clinical Research and Innovation Centre (Smith), Aneurin Bevan University Health Board, Newport, United Kingdom.
Alexander SmithFrom the College of Medicine and Pharmacy (Azhari), Umm Al-Qura University, Makkah, Kingdom of Saudi Arabia, from the School of Cardiovascular and Metabolic Health (Azhari, Quinn, Dawson), University of Glasgow, Glasgow, from the School of Geriatric Medicine Centre (Hewitt, O'Neill), Cardiff University, and from the Clinical Research and Innovation Centre (Smith), Aneurin Bevan University Health Board, Newport, United Kingdom.
Martin O'NeillFrom the College of Medicine and Pharmacy (Azhari), Umm Al-Qura University, Makkah, Kingdom of Saudi Arabia, from the School of Cardiovascular and Metabolic Health (Azhari, Quinn, Dawson), University of Glasgow, Glasgow, from the School of Geriatric Medicine Centre (Hewitt, O'Neill), Cardiff University, and from the Clinical Research and Innovation Centre (Smith), Aneurin Bevan University Health Board, Newport, United Kingdom.
Terence QuinnFrom the College of Medicine and Pharmacy (Azhari), Umm Al-Qura University, Makkah, Kingdom of Saudi Arabia, from the School of Cardiovascular and Metabolic Health (Azhari, Quinn, Dawson), University of Glasgow, Glasgow, from the School of Geriatric Medicine Centre (Hewitt, O'Neill), Cardiff University, and from the Clinical Research and Innovation Centre (Smith), Aneurin Bevan University Health Board, Newport, United Kingdom.
Jesse DawsonFrom the College of Medicine and Pharmacy (Azhari), Umm Al-Qura University, Makkah, Kingdom of Saudi Arabia, from the School of Cardiovascular and Metabolic Health (Azhari, Quinn, Dawson), University of Glasgow, Glasgow, from the School of Geriatric Medicine Centre (Hewitt, O'Neill), Cardiff University, and from the Clinical Research and Innovation Centre (Smith), Aneurin Bevan University Health Board, Newport, United Kingdom.
Umm al-Qura University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo explore the barriers preventing pioglitazone use in stroke survivors and primary and secondary stroke care services.

methodsA qualitative grounded theory approached design was used to assess post-stroke diabetes treatments and to assess clinical applicability of pioglitazone as a preventive treatment to minimize its side effects (SEs) associated. Three focus groups were established with 48 participants from Scotland and Wales health board centers during January 2019 to July 2022.

resultsA qualitative grounded theory approached design was used to assess post-stroke diabetes treatments and to assess clinical applicability of pioglitazone as a preventive treatment to minimize its SEs associated. Three focus groups were established with 48 participants from Scotland and Wales health board centers during January 2019 to July 2022.

conclusionThese strategies might allow greater treatment adherence by stroke survivors and increased confidence of the health care professionals in their practice. The findings suggest that further research will be needed to facilitate wider usage of pioglitazone in treating people with stroke and health education is necessitate when using diabetes drugs post-stroke.

Indexed as

Diabetes MellitusStrokeComorbidityHumansPioglitazoneSurvivorsPioglitazone

Identifiers

PMID38195138
PMCPMC10827012
OpenAlexW4390744368

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.