Evidence map›Paper›PMID 38195135›Full record

ArticleNeurosciences (Riyadh, Saudi Arabia)2024

Evaluation of gene-gene interaction between the interleukin (IL)-2 and IL-2RA gene polymorphisms in schizophrenia patients in the Turkish Population.

Kursat Ozdilli, Hasan Mervan Aytac, Fatima Ceren Tuncel, Yasemin Oyaci, Mustafa Pehlivan, Sacide Pehlivan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurosciences (Riyadh, Saudi Arabia), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kursat OzdilliFrom the Department of Medical Biology (Ozdilli), Faculty of Medicine, Medipol University, from the Department of Psychiatry (Aytac), Basaksehir Cam and Sakura City Hospital, University of Health Sciences, Institute of Graduate Studies in Health Sciences (Aytac, Tuncel, Oyaci, Pehlivan), Department of Medical Biology (Tuncel, Oyaci, Pehlivan), Istanbul Faculty of Medicine, Istanbul University, and from Department of Hematology (Pehlivan M), Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey.
Hasan Mervan AytacFrom the Department of Medical Biology (Ozdilli), Faculty of Medicine, Medipol University, from the Department of Psychiatry (Aytac), Basaksehir Cam and Sakura City Hospital, University of Health Sciences, Institute of Graduate Studies in Health Sciences (Aytac, Tuncel, Oyaci, Pehlivan), Department of Medical Biology (Tuncel, Oyaci, Pehlivan), Istanbul Faculty of Medicine, Istanbul University, and from Department of Hematology (Pehlivan M), Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey.ORCID https://orcid.org/0000-0002-1053-6808
Fatima Ceren TuncelFrom the Department of Medical Biology (Ozdilli), Faculty of Medicine, Medipol University, from the Department of Psychiatry (Aytac), Basaksehir Cam and Sakura City Hospital, University of Health Sciences, Institute of Graduate Studies in Health Sciences (Aytac, Tuncel, Oyaci, Pehlivan), Department of Medical Biology (Tuncel, Oyaci, Pehlivan), Istanbul Faculty of Medicine, Istanbul University, and from Department of Hematology (Pehlivan M), Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey.
Yasemin OyaciFrom the Department of Medical Biology (Ozdilli), Faculty of Medicine, Medipol University, from the Department of Psychiatry (Aytac), Basaksehir Cam and Sakura City Hospital, University of Health Sciences, Institute of Graduate Studies in Health Sciences (Aytac, Tuncel, Oyaci, Pehlivan), Department of Medical Biology (Tuncel, Oyaci, Pehlivan), Istanbul Faculty of Medicine, Istanbul University, and from Department of Hematology (Pehlivan M), Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey.
Mustafa PehlivanFrom the Department of Medical Biology (Ozdilli), Faculty of Medicine, Medipol University, from the Department of Psychiatry (Aytac), Basaksehir Cam and Sakura City Hospital, University of Health Sciences, Institute of Graduate Studies in Health Sciences (Aytac, Tuncel, Oyaci, Pehlivan), Department of Medical Biology (Tuncel, Oyaci, Pehlivan), Istanbul Faculty of Medicine, Istanbul University, and from Department of Hematology (Pehlivan M), Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey.
Sacide PehlivanFrom the Department of Medical Biology (Ozdilli), Faculty of Medicine, Medipol University, from the Department of Psychiatry (Aytac), Basaksehir Cam and Sakura City Hospital, University of Health Sciences, Institute of Graduate Studies in Health Sciences (Aytac, Tuncel, Oyaci, Pehlivan), Department of Medical Biology (Tuncel, Oyaci, Pehlivan), Istanbul Faculty of Medicine, Istanbul University, and from Department of Hematology (Pehlivan M), Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the genetic polymorphisms in

methodsA sample of 127 patients with SCZ and 100 healthy volunteers were included in the case-control study. These individuals were consecutively selected from the Malazgirt State Hospital Psychiatry Outpatient Clinic in Mus, Turkey, over the three months from October 2020 to December 2020. The Structured Clinical Interview for DSM-5 Disorders, Clinician Version (SCID-5-CV) was used to confirm the diagnosis according to the DSM-5 criteria. In addition, polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was used to determine gene polymorphisms from DNA material.

resultsOur findings indicated significant differences in the

conclusionIn light of the analyses, our study indicates that while the

Indexed as

Interleukin-2SchizophreniaAnimalsCase-Control StudiesEpistasis, GeneticHumansMicePolymorphism, GeneticReceptors, Interleukin-2TurkeyIL2 protein, humanInterleukin-2Receptors, Interleukin-2

Identifiers

PMID38195135
PMCPMC10827018

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.