ArticleNeurosciences (Riyadh, Saudi Arabia)2024
Effects of decompressive craniectomy combined with edaravone on postoperative neurological functions and hemodynamics of patients with severe traumatic brain injury.
Article in Neurosciences (Riyadh, Saudi Arabia), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 0 citations in OpenAlex.
- Edaravone: Advances on cytoprotective effects, pharmacological properties, and mechanisms of action.Pharmacological reviews · 2026Review
- Effect of early stepwise controlled decompression combined with mild hypothermia therapy on efficacy, cerebral edema volume, and serum biochemical indices in patients with severe hypertensive intracerebral hemorrhage.American journal of translational research · 2025Article
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1 author at 1 institution in 1 country.
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Abstract
objectivesTo assess the effects of decompressive craniectomy combined with edaravone on the postoperative neurological functions and hemodynamics of patients with severe traumatic brain injury (STBI).
methodsThe subjects included totally 186 STBI patients admitted during January 2018 and January 2021. The random number table method was adopted to set an operation group (n=82) and a combined medication group (n=104) for the subjects. The changes of the clinical indicators were observed.
resultsCompared with the operation group, the combined medication group had higher Neurobehavioral Cognitive Status Examination score, Barthel index score, total response rate and heart rate (
conclusionEdaravone in combination with decompressive craniectomy benefits the postoperative improvement of neurological functions of STBI patients, effectively stabilizes the hemodynamics, induces few complications and improves the prognosis.
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