Evidence map›Paper›PMID 38195062›Full record

ArticleOpen biology2024

Human growth factor-mediated signalling through lipid rafts regulates stem cell proliferation, development and survival of

Shradha Maharjan, Ruth S Kirk, Scott P Lawton, Anthony J Walker

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.6field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Shradha MaharjanMolecular Parasitology Laboratory, School of Life Sciences, Pharmacy and Chemistry, Kingston University, Penrhyn Road, Kingston upon Thames KT1 2EE, UK.
Ruth S KirkMolecular Parasitology Laboratory, School of Life Sciences, Pharmacy and Chemistry, Kingston University, Penrhyn Road, Kingston upon Thames KT1 2EE, UK.ORCID 0000-0003-3739-2530
Scott P LawtonCentre for Epidemiology and Planetary Health, SRUC School of Veterinary Medicine, Scotland's Rural College, West Mains Road, Edinburgh EH9 3JG, UK.
Anthony J WalkerMolecular Parasitology Laboratory, School of Life Sciences, Pharmacy and Chemistry, Kingston University, Penrhyn Road, Kingston upon Thames KT1 2EE, UK.ORCID 0000-0001-8549-7156
Kingston University · GBScotland's Rural College · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

Although the mechanisms by which schistosomes grow and develop in humans are poorly defined, their unique outer tegument layer, which interfaces with host blood, is considered vital to homeostasis of the parasite. Here, we investigated the importance of tegument lipid rafts to the biology of

Indexed as

Epidermal Growth FactorSchistosoma mansoniAnimalsCell ProliferationExtracellular Signal-Regulated MAP KinasesHumansSignal TransductionEpidermal Growth FactorExtracellular Signal-Regulated MAP Kinasesepidermal growth factor receptorinsulin receptorlipid raftsprotein kinaseschistosomeschistosomiasis

Identifiers

PMID38195062
PMCPMC10776228
OpenAlexW4390690294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.