Evidence map›Paper›PMID 38194495›Full record

ArticleThe Journal of international medical research2024

Efficiency of continuous positive airway pressure and high-flow nasal oxygen therapy in critically ill patients with COVID-19.

Corina Manole, Mihaela Dediu-Anghel, Liliana Baroiu, Ioana Anca Ștefanopol, Alexandru Nechifor, Elena Niculet, Raul Mihailov, Lavinia Alexandra Moroianu, Doina Carina Voinescu, Dorel Firescu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of international medical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Corina ManoleClinical Medical Department, Faculty of Medicine and Pharmacy, "Dunărea de Jos" University of Galat,i, Romania.
Mihaela Dediu-AnghelClinical Medical Department, Faculty of Medicine and Pharmacy, "Dunărea de Jos" University of Galat,i, Romania.
Liliana BaroiuClinical Medical Department, Faculty of Medicine and Pharmacy, "Dunărea de Jos" University of Galat,i, Romania.
Ioana Anca ȘtefanopolClinical Surgical Department, Faculty of Medicine and Pharmacy, "Dunărea de Jos" University of Galat,i, Romania.
Alexandru NechiforClinical Medical Department, Faculty of Medicine and Pharmacy, "Dunărea de Jos" University of Galat,i, Romania.
Elena NiculetDepartment of Morphological and Functional Sciences, Faculty of Medicine and Pharmacy, "Dunărea de Jos" University of Galat,i, Romania.ORCID 0000-0001-9249-5247
Raul MihailovDepartment of Morphological and Functional Sciences, Faculty of Medicine and Pharmacy, "Dunărea de Jos" University of Galat,i, Romania.
Lavinia Alexandra MoroianuClinical Medical Department, Faculty of Medicine and Pharmacy, "Dunărea de Jos" University of Galat,i, Romania.
Doina Carina VoinescuClinical Medical Department, Faculty of Medicine and Pharmacy, "Dunărea de Jos" University of Galat,i, Romania.
Dorel FirescuClinical Surgical Department, Faculty of Medicine and Pharmacy, "Dunărea de Jos" University of Galat,i, Romania.
"Dunarea de Jos" University of Galati · ROClinical Emergency Hospital Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCritically ill patients with COVID-19 develop acute respiratory distress syndrome characterized by relatively well-preserved pulmonary compliance but severe hypoxemia. The challenge in managing such patients lies in optimizing oxygenation, which can be achieved through either high oxygen flow or noninvasive mechanical ventilation. This study was performed to compare the efficiency of two methods of noninvasive oxygen therapy: continuous positive airway pressure (CPAP) and high-flow nasal oxygen therapy (HFNO).

methodsThis retrospective cohort study involved 668 patients hospitalized in the intensive care unit (ICU) of the "Sf. Apostol Andrei" Emergency Clinical Hospital, Galati, Romania from 1 April 2020 to 31 March 2021 (CPAP, n = 108; HFNO, n = 108).

resultsMortality was significantly lower in the CPAP and HFNO groups than in the group of patients who underwent intubation and mechanical ventilation after ICU admission. Mortality in the ICU was not significantly different between the CPAP and HFNO groups.

conclusionsHFNO and CPAP represent efficient alternative therapies for patients with severe COVID-19 whose respiratory treatment has failed. Studies involving larger groups of patients are necessary to establish a personalized, more complex management modality for critically ill patients with COVID-19.

Indexed as

COVID-19OxygenContinuous Positive Airway PressureCritical IllnessHumansRetrospective StudiesOxygenacute respiratory distress syndromecontinuous positive airway pressureCOVID-19high-flow nasal oxygen therapyhypoxemiasurvival

Identifiers

PMID38194495
PMCPMC10777799
OpenAlexW4390768223

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.