Evidence map›Paper›PMID 38194426›Full record

ReviewPloS one2024

Optimizing CO2 field flooding during sternotomy: In vitro confirmation of the Karolinska studies.

Mira Puthettu, Stijn Vandenberghe, Spyros Balafas, Clelia Di Serio, Geni Singjeli, Alberto Pagnamenta, Stefanos Demertzis

Abstract readReview
In one paragraph

Review in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mira PuthettuDepartment of Cardiac Surgery, Istituto Cardiocentro Ticino, Lugano, Switzerland.ORCID 0000-0003-1328-8974
Stijn VandenbergheDepartment of Cardiac Surgery, Istituto Cardiocentro Ticino, Lugano, Switzerland.ORCID 0000-0003-1464-0597
Spyros BalafasUniversity Centre for Statistics in the Biomedical Sciences, Vita-Salute San Raffaele University, Milano, Italy.ORCID 0000-0003-1590-2093
Clelia Di SerioFaculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland.
Geni SingjeliDepartment of Cardiac Surgery, Istituto Cardiocentro Ticino, Lugano, Switzerland.
Alberto PagnamentaClinical Trial Unit (CTU), Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland.
Stefanos DemertzisDepartment of Cardiac Surgery, Istituto Cardiocentro Ticino, Lugano, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although CO2 field-flooding was first used during cardiac surgery more than 60 years ago, its efficacy is still disputed. The invisible nature of the gas and the difficulty in determining the "safe" quantity to protect the patient are two of the main obstacles to overcome for its validation. Moreover, CO2 concentration in the chest cavity is highly sensitive to procedural aspects, such suction and hand movements. Based on our review of the existing literature, we identified four major factors that influence the intra-cavity CO2 concentration during open-heart surgery: type of delivery device (diffuser), delivery CO2 flow rate, diffuser position around the wound cavity, and its orientation inside the cavity. In this initial study, only steady state conditions were considered to establish a basic understanding on the effect of the four above-mentioned factors. Transient factors, such as suction or hand movements, will be reported separately.

Indexed as

Carbon DioxideSternotomyDissent and DisputesFloodsHandHumansCarbon Dioxide

Identifiers

PMID38194426
PMCPMC10775975

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.