Evidence map›Paper›PMID 38193984›Full record

ArticleMolecular neurobiology2024

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Xingwei Wu, Minjie Fu, Chang Ge, Hanyu Zhou, Haoyu Huang, Min Zhong, Mengying Zhang, Hao Xu, Guoping Zhu, Wei Hua and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 2 pooled it
15.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 64 citations in OpenAlex.

  1. Pooled it
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  7. Nanotechnology Meets Immunotherapy: Crosstalks Against Cancer.Immunity, inflammation and disease · 2026
    Review
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  9. Journal of translational medicine · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Xingwei Wu *Anhui Province Key Laboratory of Non-Coding RNA Basic Research and Clinical Transformation, Wannan Medical College, Wuhu, 241001, China.
Minjie Fu *Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Chang Ge *Department of Psychology, Zhejiang Sci-Tech University, Hangzhou, 310000, Zhejiang, China.
Hanyu ZhouAnhui Province Key Laboratory of Non-Coding RNA Basic Research and Clinical Transformation, Wannan Medical College, Wuhu, 241001, China.
Haoyu HuangAnhui Province Key Laboratory of Non-Coding RNA Basic Research and Clinical Transformation, Wannan Medical College, Wuhu, 241001, China.
Min ZhongAnhui Province Key Laboratory of Non-Coding RNA Basic Research and Clinical Transformation, Wannan Medical College, Wuhu, 241001, China.
Mengying ZhangAnhui Province Key Laboratory of Non-Coding RNA Basic Research and Clinical Transformation, Wannan Medical College, Wuhu, 241001, China.
Hao XuDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Guoping ZhuAnhui Provincial Key Laboratory of Molecular Enzymology and Mechanism of Major Diseases, College of Life Sciences, Anhui Normal University, Wuhu, 241001, Anhui, China. gpz2012@ahnu.edu.cn.
Wei HuaDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, 200040, China. hs_huawei@126.com.
Kun LvAnhui Province Key Laboratory of Non-Coding RNA Basic Research and Clinical Transformation, Wannan Medical College, Wuhu, 241001, China. lvkun315@126.com.
Hui YangAnhui Province Key Laboratory of Non-Coding RNA Basic Research and Clinical Transformation, Wannan Medical College, Wuhu, 241001, China. yanghui0203@wnmc.edu.cn.ORCID http://orcid.org/0000-0002-5307-3970
Wannan Medical College · CNFudan University · CNAnhui Normal University · CNZhejiang Sci-Tech University · CN

Funding

National Nature Science Foundation of China 81772180National Nature Science Foundation of China 81802503National Nature Science Foundation of China 82072370
6 · The paper itself

Abstract

Long noncoding RNAs (lncRNAs) play crucial roles in tumor progression and are dysregulated in glioma. However, the functional roles of lncRNAs in glioma remain largely unknown. In this study, we utilized the TCGA (the Cancer Genome Atlas database) and GEPIA2 (Gene Expression Profiling Interactive Analysis 2) databases and observed the overexpression of lncRNA CHASERR in glioma tissues. We subsequently investigated this phenomenon in glioma cell lines. The effects of lncRNA CHASERR on glioma proliferation, migration, and invasion were analyzed using in vitro and in vivo experiments. Additionally, the regulatory mechanisms among PTEN/p-Akt/mTOR and Wnt/β-catenin, lncRNA CHASERR, Micro-RNA-6893-3p(miR-6893-3p), and tripartite motif containing14 (TRIM14) were investigated via bioinformatics analyses, quantitative real-time PCR (qRT-PCR), western blot (WB), RNA immunoprecipitation (RIP), dual luciferase reporter assay, fluorescence in situ hybridization (FISH), and RNA sequencing assays. RIP and RT-qRCR were used to analyze the regulatory effect of N

Indexed as

Disease ProgressionGene Expression Regulation, NeoplasticGliomaMicroRNAsRNA, Long NoncodingTripartite Motif ProteinsUp-RegulationAdenosineAnimalsBrain NeoplasmsCarrier ProteinsCell Line, TumorCell MovementCell ProliferationHumansIntracellular Signaling Peptides and ProteinsAdenosineCarrier ProteinsIntracellular Signaling Peptides and ProteinsMicroRNAsN-methyladenosineRNA, Long NoncodingTRIM14 protein, humanTripartite Motif ProteinsGliomalncRNA CHASERRmiR-6893-3pN 6-methyladenosineTRIM14

Identifiers

PMID38193984
OpenAlexW4390779166

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.