ArticleACS applied bio materials2024
Bacteria Colonies Modify Their Shear and Compressive Mechanical Properties in Response to Different Growth Substrates.
Article in ACS applied bio materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- The EPS-I exopolysaccharide transformsProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Mechanotransduction in Shaping Immunity: Pathways, Crosstalk, and Pathophysiological Relevance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Magnetically Tunable Hydrogel for Biofilm Control.ACS applied bio materials · 2025Article
- Rheological Investigation of Polydimethylsiloxane with Glass Beads: A Model for Compression-Stiffening Effects in Soft Tissue Engineering.Materials (Basel, Switzerland) · 2025Article
- Substrate stiffness modulates collective colony expansion of the social bacteriumAPL bioengineering · 2025Article
- Impact of MSMEG5257 Deletion onMicroorganisms · 2024Article
- Bacterial Persister Cells and Development of Antibiotic Resistance in Chronic Infections: An Update.British journal of biomedical science · 2024Review
Corrections and comments
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Authors and funding
5 authors.
Funding
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Abstract
Bacteria build multicellular communities termed biofilms, which are often encased in a self-secreted extracellular matrix that gives the community mechanical strength and protection against harsh chemicals. How bacteria assemble distinct multicellular structures in response to different environmental conditions remains incompletely understood. Here, we investigated the connection between bacteria colony mechanics and the colony growth substrate by measuring the oscillatory shear and compressive rheology of bacteria colonies grown on agar substrates. We found that bacteria colonies modify their own mechanical properties in response to shear and uniaxial compression in a manner that depends on the concentration of agar in their growth substrate. These findings highlight that mechanical interactions between bacteria and their microenvironments are an important element in bacteria colony development, which can aid in developing strategies to disrupt or reduce biofilm growth.
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Registered trials
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