ArticleMicrobiology spectrum2024
Reduced olfactory performance is associated with changed microbial diversity, oralization, and accumulation of dead biomaterial in the nasal olfactory area.
Article in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Microbiome and well-being: a meta-analysis.NPJ biofilms and microbiomes · 2025Pooled it
- Clinical and Immunological Perspectives on the Nasal Microbiome's Role in Olfactory Function and Dysfunction.Microorganisms · 2026Review
- Machine learning elucidates associations between oral microbiota and the decline of sweet taste perception during aging.NPJ science of food · 2026Article
- The microbiota-metabolite-immune axis in the olfactory cleft microenvironment: mechanisms and therapeutic implications for dysbiosis-driven olfactory dysfunction in chronic rhinosinusitis.Frontiers in immunology · 2026Review
- A Narrative Review on the Role of Microbiota and Microglia in Premotor Symptoms of Parkinson's Disease.Neurotoxicity research · 2025Review
- Exploring the human archaeome: its relevance for health and disease, and its complex interplay with the human immune system.The FEBS journal · 2025Review
- Periodontitis is associated with impaired olfactory function: A clinical study.Journal of periodontal research · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
The partial or complete loss of the sense of smell, which affects about 20% of the population, impairs the quality of life in many ways. Dysosmia and anosmia are mainly caused by aging, trauma, infections, or even neurodegenerative disease. Recently, the olfactory area-a site containing the olfactory receptor cells responsible for odor perception-was shown to harbor a complex microbiome that reflects the state of olfactory function. This initially observed correlation between microbiome composition and olfactory performance needed to be confirmed using a larger study cohort and additional analyses. A total of 120 participants (middle-aged, no neurodegenerative disease) were enrolled in the study to further analyze the microbial role in human olfactory function. Olfactory performance was assessed using the Sniffin' Stick battery, and participants were grouped accordingly (normosmia:
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Registered trials
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